HCSGD entry for PCCA
1. General information
| Official gene symbol | PCCA |
|---|---|
| Entrez ID | 5095 |
| Gene full name | propionyl CoA carboxylase, alpha polypeptide |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004075 | Biotin carboxylase activity | IEA | molecular_function |
| GO:0004658 | Propionyl-CoA carboxylase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006635 | Fatty acid beta-oxidation | TAS | biological_process |
| GO:0006766 | Vitamin metabolic process | TAS | biological_process |
| GO:0006767 | Water-soluble vitamin metabolic process | TAS | biological_process |
| GO:0006768 | Biotin metabolic process | TAS | biological_process |
| GO:0009374 | Biotin binding | TAS | molecular_function |
| GO:0019626 | Short-chain fatty acid catabolic process | TAS | biological_process |
| GO:0019836 | Hemolysis by symbiont of host erythrocytes | IEA | biological_process |
| GO:0019899 | Enzyme binding | IPI | molecular_function |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9842970480 | 0.0448937198 | 0.9999902473 | 0.3985320742 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1030918891 |
| GSE13712_SHEAR | Down | -0.1401741224 |
| GSE13712_STATIC | Down | -0.2077852777 |
| GSE19018 | Down | -0.0807256378 |
| GSE19899_A1 | Down | -0.2275604124 |
| GSE19899_A2 | Down | -0.4913160330 |
| PubMed_21979375_A1 | Down | -0.5782071115 |
| PubMed_21979375_A2 | Down | -0.2404287215 |
| GSE35957 | Down | -0.2900829737 |
| GSE36640 | Down | -0.0844273834 |
| GSE54402 | Down | -0.0451524500 |
| GSE9593 | Down | -0.1799233904 |
| GSE43922 | Down | -0.7684208191 |
| GSE24585 | Up | 0.0499939414 |
| GSE37065 | Up | 0.0991867069 |
| GSE28863_A1 | Up | 0.1232654169 |
| GSE28863_A2 | Down | -0.3619512554 |
| GSE28863_A3 | Down | -0.3583343057 |
| GSE28863_A4 | Up | 0.0584494218 |
| GSE48662 | Down | -0.3868497089 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029589 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-455-5p | MIMAT0003150 | MIRT040742 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
