HCSGD entry for PDE11A
1. General information
| Official gene symbol | PDE11A |
|---|---|
| Entrez ID | 50940 |
| Gene full name | phosphodiesterase 11A |
| Other gene symbols | PPNAD2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004112 | Cyclic-nucleotide phosphodiesterase activity | NAS | molecular_function |
| GO:0004114 | 3',5'-cyclic-nucleotide phosphodiesterase activity | IEA TAS | molecular_function |
| GO:0004118 | CGMP-stimulated cyclic-nucleotide phosphodiesterase activity | IDA | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006198 | CAMP catabolic process | IEA | biological_process |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0030552 | CAMP binding | IEA | molecular_function |
| GO:0030553 | CGMP binding | IDA IEA | molecular_function |
| GO:0043204 | Perikaryon | IEA | cellular_component |
| GO:0046069 | CGMP catabolic process | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0838108355 | 0.3543034839 | 0.6094297514 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1087394074 |
| GSE13712_SHEAR | Up | 0.0244975533 |
| GSE13712_STATIC | Down | -0.1346132310 |
| GSE19018 | Up | 0.2999949617 |
| GSE19899_A1 | Up | 0.0670532317 |
| GSE19899_A2 | Up | 0.0929634077 |
| PubMed_21979375_A1 | Down | -0.1383455069 |
| PubMed_21979375_A2 | Down | -0.0458019539 |
| GSE35957 | Up | 1.4692606383 |
| GSE36640 | Up | 1.5694624664 |
| GSE54402 | Down | -0.0560734145 |
| GSE9593 | Up | 0.0492102827 |
| GSE43922 | Up | 0.0118275794 |
| GSE24585 | Up | 0.5739347237 |
| GSE37065 | Down | -0.0974774998 |
| GSE28863_A1 | Down | -0.8995328553 |
| GSE28863_A2 | Up | 0.4741931698 |
| GSE28863_A3 | Down | -0.7427419296 |
| GSE28863_A4 | Up | 0.0423827212 |
| GSE48662 | Up | 0.5513767389 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029552 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
