HCSGD entry for ATP5C1
1. General information
| Official gene symbol | ATP5C1 |
|---|---|
| Entrez ID | 509 |
| Gene full name | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 |
| Other gene symbols | ATP5C ATP5CL1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000275 | Mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) | NAS | cellular_component |
| GO:0005739 | Mitochondrion | ISS NAS | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA ISS | cellular_component |
| GO:0005753 | Mitochondrial proton-transporting ATP synthase complex | IDA | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006119 | Oxidative phosphorylation | NAS | biological_process |
| GO:0006200 | ATP catabolic process | IDA NAS | biological_process |
| GO:0006754 | ATP biosynthetic process | NAS | biological_process |
| GO:0015986 | ATP synthesis coupled proton transport | IEA | biological_process |
| GO:0016887 | ATPase activity | IDA NAS | molecular_function |
| GO:0022857 | Transmembrane transporter activity | IC | molecular_function |
| GO:0022904 | Respiratory electron transport chain | TAS | biological_process |
| GO:0042776 | Mitochondrial ATP synthesis coupled proton transport | IC TAS | biological_process |
| GO:0044237 | Cellular metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045261 | Proton-transporting ATP synthase complex, catalytic core F(1) | IEA | cellular_component |
| GO:0046933 | Proton-transporting ATP synthase activity, rotational mechanism | IEA | molecular_function |
| GO:0046961 | Proton-transporting ATPase activity, rotational mechanism | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9640561567 | 0.1203593063 | 0.9999902473 | 0.6662412829 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0964097258 |
| GSE13712_SHEAR | Down | -0.0201235564 |
| GSE13712_STATIC | Down | -0.0116866726 |
| GSE19018 | Up | 0.0486324074 |
| GSE19899_A1 | Down | -0.0412877679 |
| GSE19899_A2 | Down | -0.4818280528 |
| PubMed_21979375_A1 | Down | -0.3057331664 |
| PubMed_21979375_A2 | Down | -0.1208733056 |
| GSE35957 | Down | -0.4841185934 |
| GSE36640 | Up | 0.0400468484 |
| GSE54402 | Down | -0.0915053773 |
| GSE9593 | Down | -0.3598248087 |
| GSE43922 | Down | -0.1539756212 |
| GSE24585 | Down | -0.1181190782 |
| GSE37065 | Up | 0.0380918831 |
| GSE28863_A1 | Down | -0.0231571436 |
| GSE28863_A2 | Up | 0.1952111529 |
| GSE28863_A3 | Down | -0.5028179495 |
| GSE28863_A4 | Up | 0.1107416149 |
| GSE48662 | Down | -0.4751267050 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Quercetin | DB04216 | EXPT02732 |
| 1-ACETYL-2-CARBOXYPIPERIDINE | DB07384 | - |
| AUROVERTIN B | DB07394 | - |
| PICEATANNOL | DB08399 | - |
| N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE | DB08629 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30b-5p | MIMAT0000420 | MIRT046113 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051299 | CLASH | Functional MTI (Weak) | 23622248 |
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