HCSGD entry for AK3
1. General information
| Official gene symbol | AK3 |
|---|---|
| Entrez ID | 50808 |
| Gene full name | adenylate kinase 3 |
| Other gene symbols | AK3L1 AK6 AKL3L AKL3L1 FIX |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004017 | Adenylate kinase activity | IDA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | ISS | cellular_component |
| GO:0005759 | Mitochondrial matrix | ISS TAS | cellular_component |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0046033 | AMP metabolic process | IDA | biological_process |
| GO:0046039 | GTP metabolic process | IDA | biological_process |
| GO:0046041 | ITP metabolic process | IDA | biological_process |
| GO:0046051 | UTP metabolic process | IDA | biological_process |
| GO:0046899 | Nucleoside triphosphate adenylate kinase activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0201476692 | 0.9806483948 | 0.3420940722 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2235032944 |
| GSE13712_SHEAR | Down | -0.0494176685 |
| GSE13712_STATIC | Down | -0.0481053727 |
| GSE19018 | Up | 0.1748730812 |
| GSE19899_A1 | Up | 0.5201795411 |
| GSE19899_A2 | Up | 0.5457984787 |
| PubMed_21979375_A1 | Down | -0.5189781820 |
| PubMed_21979375_A2 | Up | 0.5294429237 |
| GSE35957 | Up | 0.7024215719 |
| GSE36640 | Up | 1.2518932663 |
| GSE54402 | Down | -0.5049902570 |
| GSE9593 | Up | 0.4100615387 |
| GSE43922 | Up | 0.2053383489 |
| GSE24585 | Up | 0.1875214229 |
| GSE37065 | Up | 0.0962530321 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.3201211899 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022580 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030501 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043088 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-197-3p | MIMAT0000227 | MIRT048103 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
