HCSGD entry for ASAP1


1. General information

Official gene symbolASAP1
Entrez ID50807
Gene full nameArfGAP with SH3 domain, ankyrin repeat and PH domain 1
Other gene symbolsAMAP1 CENTB4 DDEF1 PAG2 PAP ZG14P
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0008060ARF GTPase activator activityIEAmolecular_function
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0016020MembraneIEAcellular_component
GO:0032312Regulation of ARF GTPase activityIEAbiological_process
GO:0060271Cilium morphogenesisIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.79674046960.03059212800.99999024730.3301596311

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.5855419328
GSE13712_SHEARUp0.3731837237
GSE13712_STATICUp0.5003167206
GSE19018Up0.0005656607
GSE19899_A1Down-0.7089085853
GSE19899_A2Down-0.0037747813
PubMed_21979375_A1Down-0.4299368160
PubMed_21979375_A2Down-0.2164169817
GSE35957Up0.3859791185
GSE36640Down-0.3876425539
GSE54402Down-0.3665739298
GSE9593Up0.4560898337
GSE43922Down-0.2951208146
GSE24585Down-0.4305717762
GSE37065Down-0.1376016355
GSE28863_A1Up0.2326416413
GSE28863_A2Up0.2811145867
GSE28863_A3Down-0.3898505415
GSE28863_A4Down-0.0195855318
GSE48662Down-0.8224443172

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-98-5pMIMAT0000096MIRT027690MicroarrayFunctional MTI (Weak)19088304
hsa-miR-32-5pMIMAT0000090MIRT028337SequencingFunctional MTI (Weak)20371350
hsa-miR-106b-5pMIMAT0000680MIRT044301CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.