HCSGD entry for IRX4
1. General information
| Official gene symbol | IRX4 |
|---|---|
| Entrez ID | 50805 |
| Gene full name | iroquois homeobox 4 |
| Other gene symbols | IRXA3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0007507 | Heart development | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0048561 | Establishment of organ orientation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4088528741 | 0.8094500741 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0023876471 |
| GSE13712_SHEAR | Down | -0.0504488819 |
| GSE13712_STATIC | Down | -0.0703203517 |
| GSE19018 | Down | -0.0016210341 |
| GSE19899_A1 | Down | -0.0738567903 |
| GSE19899_A2 | Up | 0.2040232866 |
| PubMed_21979375_A1 | Up | 0.1452730942 |
| PubMed_21979375_A2 | Up | 0.2855076696 |
| GSE35957 | Down | -0.0015000537 |
| GSE36640 | Down | -0.1340449064 |
| GSE54402 | Down | -0.0165108160 |
| GSE9593 | Up | 0.1208137986 |
| GSE43922 | Up | 0.0437451253 |
| GSE24585 | Down | -0.1063665467 |
| GSE37065 | Down | -0.1242290252 |
| GSE28863_A1 | Down | -0.1278710383 |
| GSE28863_A2 | Up | 0.0957805868 |
| GSE28863_A3 | Up | 0.4753478956 |
| GSE28863_A4 | Up | 0.2604640260 |
| GSE48662 | Up | 0.0155866784 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024687 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026778 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
