HCSGD entry for PAX4

1. General information

Official gene symbolPAX4
Entrez ID5078
Gene full namepaired box 4
Other gene symbolsKPD MODY9
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0003677DNA bindingTASmolecular_function
GO:0003690Double-stranded DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0007623Circadian rhythmIEAbiological_process
GO:0009887Organ morphogenesisTASbiological_process
GO:0030154Cell differentiationIEAbiological_process
GO:0031018Endocrine pancreas developmentTASbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045597Positive regulation of cell differentiationIEAbiological_process
GO:0051591Response to cAMPIEAbiological_process
GO:0060041Retina development in camera-type eyeIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.63428151670.89901885570.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0276470110
GSE13712_SHEARDown-0.0387807591
GSE13712_STATICUp0.0320959687
GSE19018Up0.0149237228
GSE19899_A1Up0.0156935746
GSE19899_A2Up0.0011027891
PubMed_21979375_A1Up0.0777174056
PubMed_21979375_A2Up0.0520245235
GSE35957Up0.2077392039
GSE36640Up0.0005273372
GSE54402Down-0.0827561071
GSE9593Down-0.0225393451
GSE43922Up0.0894521599
GSE24585Down-0.0656579505
GSE37065Down-0.0567595410
GSE28863_A1Down-0.0705053812
GSE28863_A2Down-0.0129499542
GSE28863_A3Up0.1552992702
GSE28863_A4Up0.0593029603
GSE48662Up0.5350645562

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.