HCSGD entry for IL22
1. General information
| Official gene symbol | IL22 |
|---|---|
| Entrez ID | 50616 |
| Gene full name | interleukin 22 |
| Other gene symbols | IL-21 IL-22 IL-D110 IL-TIF ILTIF TIFIL-23 TIFa zcyto18 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005125 | Cytokine activity | IEA | molecular_function |
| GO:0005576 | Extracellular region | IC | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0006953 | Acute-phase response | NAS | biological_process |
| GO:0006954 | Inflammatory response | NAS | biological_process |
| GO:0007267 | Cell-cell signaling | IC | biological_process |
| GO:0045518 | Interleukin-22 receptor binding | NAS | molecular_function |
| GO:0051384 | Response to glucocorticoid | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7520214885 | 0.8125529311 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1423885546 |
| GSE13712_SHEAR | Down | -0.2384794932 |
| GSE13712_STATIC | Up | 0.0276002508 |
| GSE19018 | Up | 0.1071562649 |
| GSE19899_A1 | Up | 0.0348226066 |
| GSE19899_A2 | Up | 0.0456276473 |
| PubMed_21979375_A1 | Down | -0.0246777841 |
| PubMed_21979375_A2 | Down | -0.0745436133 |
| GSE35957 | Up | 0.1112709255 |
| GSE36640 | Up | 0.0915454288 |
| GSE54402 | Down | -0.0017415959 |
| GSE9593 | Down | -0.0654029312 |
| GSE43922 | Up | 0.0191703173 |
| GSE24585 | Down | -0.0213378099 |
| GSE37065 | Up | 0.0256892003 |
| GSE28863_A1 | Down | -0.0246618972 |
| GSE28863_A2 | Up | 0.1428946274 |
| GSE28863_A3 | Up | 0.1085650805 |
| GSE28863_A4 | Up | 0.0269859578 |
| GSE48662 | Down | -0.0837356554 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017094 | Microarray | Functional MTI (Weak) | 18185580 |
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