HCSGD entry for IL22


1. General information

Official gene symbolIL22
Entrez ID50616
Gene full nameinterleukin 22
Other gene symbolsIL-21 IL-22 IL-D110 IL-TIF ILTIF TIFIL-23 TIFa zcyto18
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005125Cytokine activityIEAmolecular_function
GO:0005576Extracellular regionICcellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0006953Acute-phase responseNASbiological_process
GO:0006954Inflammatory responseNASbiological_process
GO:0007267Cell-cell signalingICbiological_process
GO:0045518Interleukin-22 receptor bindingNASmolecular_function
GO:0051384Response to glucocorticoidIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.75202148850.81255293110.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1423885546
GSE13712_SHEARDown-0.2384794932
GSE13712_STATICUp0.0276002508
GSE19018Up0.1071562649
GSE19899_A1Up0.0348226066
GSE19899_A2Up0.0456276473
PubMed_21979375_A1Down-0.0246777841
PubMed_21979375_A2Down-0.0745436133
GSE35957Up0.1112709255
GSE36640Up0.0915454288
GSE54402Down-0.0017415959
GSE9593Down-0.0654029312
GSE43922Up0.0191703173
GSE24585Down-0.0213378099
GSE37065Up0.0256892003
GSE28863_A1Down-0.0246618972
GSE28863_A2Up0.1428946274
GSE28863_A3Up0.1085650805
GSE28863_A4Up0.0269859578
GSE48662Down-0.0837356554

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017094MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.