HCSGD entry for IL21R


1. General information

Official gene symbolIL21R
Entrez ID50615
Gene full nameinterleukin 21 receptor
Other gene symbolsCD360 NILR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001532Interleukin-21 receptor activityNASmolecular_function
GO:0007165Signal transductionNASbiological_process
GO:0016021Integral component of membraneNAScellular_component
GO:0019221Cytokine-mediated signaling pathwayNASbiological_process
GO:0030101Natural killer cell activationNASbiological_process
GO:0038114Interleukin-21-mediated signaling pathwayNASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.21242740780.43443940960.88821315331.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0100844631
GSE13712_SHEARDown-0.0212648550
GSE13712_STATICUp0.0539986104
GSE19018Up0.0490522672
GSE19899_A1Up0.0206094839
GSE19899_A2Down-0.0979468537
PubMed_21979375_A1Down-0.1232667116
PubMed_21979375_A2Up0.0348984317
GSE35957Up0.0214691751
GSE36640Up2.3307223446
GSE54402Down-0.1502077779
GSE9593Up0.0496221772
GSE43922Up0.2563221236
GSE24585Down-0.0461136222
GSE37065Down-0.0629447792
GSE28863_A1Down-0.3949539874
GSE28863_A2Down-0.4481464774
GSE28863_A3Up0.2421015946
GSE28863_A4Up0.2939712588
GSE48662Down-0.0819807589

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018475MicroarrayFunctional MTI (Weak)18185580
hsa-miR-148b-3pMIMAT0000759MIRT019448MicroarrayFunctional MTI (Weak)17612493
hsa-miR-7-5pMIMAT0000252MIRT025813MicroarrayFunctional MTI (Weak)17612493
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.