HCSGD entry for IL20
1. General information
| Official gene symbol | IL20 |
|---|---|
| Entrez ID | 50604 |
| Gene full name | interleukin 20 |
| Other gene symbols | IL-20 IL10D ZCYTO10 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005102 | Receptor binding | IEA | molecular_function |
| GO:0005125 | Cytokine activity | IEA | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0042517 | Positive regulation of tyrosine phosphorylation of Stat3 protein | TAS | biological_process |
| GO:0045517 | Interleukin-20 receptor binding | TAS | molecular_function |
| GO:0045518 | Interleukin-22 receptor binding | IEA | molecular_function |
| GO:0045606 | Positive regulation of epidermal cell differentiation | TAS | biological_process |
| GO:0045618 | Positive regulation of keratinocyte differentiation | TAS | biological_process |
| GO:0045672 | Positive regulation of osteoclast differentiation | IEA | biological_process |
| GO:0050727 | Regulation of inflammatory response | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7985349379 | 0.5721318415 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1082759573 |
| GSE13712_SHEAR | Up | 0.0435324172 |
| GSE13712_STATIC | Down | -0.1032248194 |
| GSE19018 | Down | -0.0894607159 |
| GSE19899_A1 | Up | 0.1863560082 |
| GSE19899_A2 | Up | 0.0412615897 |
| PubMed_21979375_A1 | Down | -0.1577543321 |
| PubMed_21979375_A2 | Down | -0.0538682421 |
| GSE35957 | Up | 0.2577315153 |
| GSE36640 | Up | 0.1561758492 |
| GSE54402 | Down | -0.0375610860 |
| GSE9593 | Up | 0.0329974513 |
| GSE43922 | Up | 0.0098671421 |
| GSE24585 | Down | -0.2490414768 |
| GSE37065 | Up | 0.0236282606 |
| GSE28863_A1 | Down | -0.2270451976 |
| GSE28863_A2 | Up | 0.0601558921 |
| GSE28863_A3 | Up | 0.1358978984 |
| GSE28863_A4 | Up | 0.1494366113 |
| GSE48662 | Down | -0.0214399292 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 19802007 | JAK1/STAT-activating ligands, interleukin 10 (IL10), IL20, IL24, interferon gamma (IFNgamma), IFNbeta and IL6, were also expressed by senescent cells, supporting autocrine/paracrine activation of JAK1/STAT |
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