HCSGD entry for ATP5B

1. General information

Official gene symbolATP5B
Entrez ID506
Gene full nameATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
Other gene symbolsATPMB ATPSB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001525AngiogenesisIMPbiological_process
GO:0005215Transporter activityNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005739MitochondrionIDAcellular_component
GO:0005753Mitochondrial proton-transporting ATP synthase complexIDAcellular_component
GO:0005754Mitochondrial proton-transporting ATP synthase, catalytic coreNAScellular_component
GO:0005759Mitochondrial matrixNAS TAScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006091Generation of precursor metabolites and energyNASbiological_process
GO:0006200ATP catabolic processIDA IMPbiological_process
GO:0006629Lipid metabolic processIEAbiological_process
GO:0006754ATP biosynthetic processIMPbiological_process
GO:0006933Negative regulation of cell adhesion involved in substrate-bound cell migrationIEAbiological_process
GO:0009986Cell surfaceIDAcellular_component
GO:0015986ATP synthesis coupled proton transportIEAbiological_process
GO:0015991ATP hydrolysis coupled proton transportIEAbiological_process
GO:0015992Proton transportIMPbiological_process
GO:0016887ATPase activityIDAmolecular_function
GO:0022857Transmembrane transporter activityICmolecular_function
GO:0022904Respiratory electron transport chainTASbiological_process
GO:0031966Mitochondrial membraneIDAcellular_component
GO:0033178Proton-transporting two-sector ATPase complex, catalytic domainIEAcellular_component
GO:0042288MHC class I protein bindingIDAmolecular_function
GO:0042645Mitochondrial nucleoidIDAcellular_component
GO:0042776Mitochondrial ATP synthesis coupled proton transportIC TASbiological_process
GO:0044237Cellular metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045261Proton-transporting ATP synthase complex, catalytic core F(1)IEAcellular_component
GO:0046933Proton-transporting ATP synthase activity, rotational mechanismIEAmolecular_function
GO:0046961Proton-transporting ATPase activity, rotational mechanismIMPmolecular_function
GO:0051453Regulation of intracellular pHIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.25724379390.84378054410.95057746741.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3794992240
GSE13712_SHEARDown-0.0875427937
GSE13712_STATICUp0.0729992512
GSE19018Up0.3325798503
GSE19899_A1Up0.1702268791
GSE19899_A2Up0.2112937907
PubMed_21979375_A1Up0.5509298970
PubMed_21979375_A2Up0.1977273365
GSE35957Down-0.2050757462
GSE36640Up0.0162113705
GSE54402Up0.2761285410
GSE9593Down-0.2049599436
GSE43922Up0.0568751621
GSE24585Up0.0483405807
GSE37065Up0.0143857587
GSE28863_A1Down-0.2589980827
GSE28863_A2Down-0.1428812671
GSE28863_A3Down-0.3171372510
GSE28863_A4Up0.0936901675
GSE48662Down-0.0761358619

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

QuercetinDB04216 EXPT02732
1-ACETYL-2-CARBOXYPIPERIDINEDB07384 -
AUROVERTIN BDB07394 -
PICEATANNOLDB08399 -
N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINEDB08629 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-101-3pMIMAT0000099MIRT005602qRT-PCR//Western blot//Reporter assay;Western blot;qRT-PCR;OtherFunctional MTI21291913
hsa-miR-193b-3pMIMAT0002819MIRT016458ProteomicsFunctional MTI (Weak)21512034
hsa-miR-320bMIMAT0005792MIRT036231CLASHFunctional MTI (Weak)23622248
hsa-miR-744-5pMIMAT0004945MIRT037390CLASHFunctional MTI (Weak)23622248
hsa-miR-423-5pMIMAT0004748MIRT038164CLASHFunctional MTI (Weak)23622248
hsa-miR-339-3pMIMAT0004702MIRT038180CLASHFunctional MTI (Weak)23622248
hsa-miR-151a-5pMIMAT0004697MIRT038192CLASHFunctional MTI (Weak)23622248
hsa-miR-652-3pMIMAT0003322MIRT039526CLASHFunctional MTI (Weak)23622248
hsa-miR-629-3pMIMAT0003298MIRT039583CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT039749CLASHFunctional MTI (Weak)23622248
hsa-miR-324-3pMIMAT0000762MIRT042953CLASHFunctional MTI (Weak)23622248
hsa-miR-324-5pMIMAT0000761MIRT043106CLASHFunctional MTI (Weak)23622248
hsa-miR-331-3pMIMAT0000760MIRT043514CLASHFunctional MTI (Weak)23622248
hsa-miR-320aMIMAT0000510MIRT044737CLASHFunctional MTI (Weak)23622248
hsa-miR-125b-5pMIMAT0000423MIRT046071CLASHFunctional MTI (Weak)23622248
hsa-miR-93-5pMIMAT0000093MIRT048763CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049370CLASHFunctional MTI (Weak)23622248
hsa-miR-24-3pMIMAT0000080MIRT050381CLASHFunctional MTI (Weak)23622248
hsa-miR-17-5pMIMAT0000070MIRT050865CLASHFunctional MTI (Weak)23622248
hsa-let-7f-5pMIMAT0000067MIRT051391CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.