HCSGD entry for NOX3
1. General information
| Official gene symbol | NOX3 |
|---|---|
| Entrez ID | 50508 |
| Gene full name | NADPH oxidase 3 |
| Other gene symbols | GP91-3 MOX-2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001659 | Temperature homeostasis | IEA | biological_process |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0009590 | Detection of gravity | IEA | biological_process |
| GO:0016175 | Superoxide-generating NADPH oxidase activity | IEA | molecular_function |
| GO:0042554 | Superoxide anion generation | IEA | biological_process |
| GO:0043020 | NADPH oxidase complex | IEA | cellular_component |
| GO:0048840 | Otolith development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6626757266 | 0.8161520953 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0449574149 |
| GSE13712_SHEAR | Up | 0.0045880288 |
| GSE13712_STATIC | Down | -0.0493863036 |
| GSE19018 | Up | 0.0893448027 |
| GSE19899_A1 | Up | 0.2591721847 |
| GSE19899_A2 | Down | -0.1010898008 |
| PubMed_21979375_A1 | Up | 0.0491365159 |
| PubMed_21979375_A2 | Up | 0.0117466849 |
| GSE35957 | Down | -0.0468617515 |
| GSE36640 | Up | 0.1757571653 |
| GSE54402 | Down | -0.0302392398 |
| GSE9593 | Up | 0.1653401931 |
| GSE43922 | Up | 0.0136828369 |
| GSE24585 | Down | -0.0715881213 |
| GSE37065 | Up | 0.0437943517 |
| GSE28863_A1 | Up | 0.0147145226 |
| GSE28863_A2 | Down | -0.0133385616 |
| GSE28863_A3 | Up | 0.0848616831 |
| GSE28863_A4 | Up | 0.0182043366 |
| GSE48662 | Down | -0.1171722069 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029921 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 21841319 | There were no significant changes in NOX1 or NOX3 |
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