HCSGD entry for P2RY6

1. General information

Official gene symbolP2RY6
Entrez ID5031
Gene full namepyrimidinergic receptor P2Y, G-protein coupled, 6
Other gene symbolsP2Y6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004930G-protein coupled receptor activityTASmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007200Phospholipase C-activating G-protein coupled receptor signaling pathwayTASbiological_process
GO:0014911Positive regulation of smooth muscle cell migrationIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016323Basolateral plasma membraneIEAcellular_component
GO:0016324Apical plasma membraneIEAcellular_component
GO:0030321Transepithelial chloride transportIEAbiological_process
GO:0045028G-protein coupled purinergic nucleotide receptor activityIEAmolecular_function
GO:0045029UDP-activated nucleotide receptor activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.55032088450.44245606170.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0656736077
GSE13712_SHEARDown-0.0447929511
GSE13712_STATICUp0.1426648470
GSE19018Up0.1189889972
GSE19899_A1Down-0.0009768414
GSE19899_A2Up0.0368468244
PubMed_21979375_A1Up0.3818747621
PubMed_21979375_A2Down-0.1654152035
GSE35957Up0.6733579847
GSE36640Down-0.0483485276
GSE54402Down-0.0571541522
GSE9593Down-0.1097016753
GSE43922Up0.1685120627
GSE24585Down-0.0504530290
GSE37065Down-0.3901508939
GSE28863_A1Down-0.1586618499
GSE28863_A2Down-0.1398535241
GSE28863_A3Up0.1241952176
GSE28863_A4Up0.1160599043
GSE48662Down-0.2099863563

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT028885MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.