HCSGD entry for OPRL1

1. General information

Official gene symbolOPRL1
Entrez ID4987
Gene full nameopiate receptor-like 1
Other gene symbolsKOR-3 NOCIR OOR ORL1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001626Nociceptin receptor activityIDAmolecular_function
GO:0004930G-protein coupled receptor activityIGI IMPmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIDAcellular_component
GO:0007193Adenylate cyclase-inhibiting G-protein coupled receptor signaling pathwayIMPbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationIGIbiological_process
GO:0007600Sensory perceptionTASbiological_process
GO:0007610BehaviorIEAbiological_process
GO:0016023Cytoplasmic membrane-bounded vesicleIEAcellular_component
GO:0019233Sensory perception of painISSbiological_process
GO:0038003Opioid receptor signaling pathwayIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.57976859160.85324272250.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0662615747
GSE13712_SHEARDown-0.1361478904
GSE13712_STATICUp0.0735895237
GSE19018Up0.0297901062
GSE19899_A1Up0.0220232563
GSE19899_A2Up0.2762665278
PubMed_21979375_A1Down-0.1468499035
PubMed_21979375_A2Up0.1470627955
GSE35957Up0.1383296561
GSE36640Up0.0999444438
GSE54402Down-0.0806308254
GSE9593Up0.0433871969
GSE43922Up0.0486209986
GSE24585Up0.0725268735
GSE37065Down-0.0463103263
GSE28863_A1Down-0.0955283545
GSE28863_A2Down-0.0972099522
GSE28863_A3Up0.3384973048
GSE28863_A4Up0.0998181718
GSE48662Up0.0171540741

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

EtorphineDB01497 -
Epicept NP-1DB05492 DB08290

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.