HCSGD entry for OGN


1. General information

Official gene symbolOGN
Entrez ID4969
Gene full nameosteoglycin
Other gene symbolsOG OIF SLRR3A
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005578Proteinaceous extracellular matrixIEAcellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0005796Golgi lumenTAScellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0008083Growth factor activityIEAmolecular_function
GO:0018146Keratan sulfate biosynthetic processTASbiological_process
GO:0030203Glycosaminoglycan metabolic processTASbiological_process
GO:0031012Extracellular matrixIDAcellular_component
GO:0042339Keratan sulfate metabolic processTASbiological_process
GO:0042340Keratan sulfate catabolic processTASbiological_process
GO:0043202Lysosomal lumenTAScellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0048662Negative regulation of smooth muscle cell proliferationISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.52731656090.36443963760.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0479409577
GSE13712_SHEARUp0.0576960293
GSE13712_STATICDown-0.0650732907
GSE19018Down-0.0116243391
GSE19899_A1Down-0.0482967378
GSE19899_A2Down-0.2156816498
PubMed_21979375_A1Up0.0438284799
PubMed_21979375_A2Up0.0492245515
GSE35957Down-0.4522697909
GSE36640Down-0.1640977283
GSE54402Up0.0452993819
GSE9593Up0.1708996504
GSE43922Up0.0214071659
GSE24585Up0.1819229628
GSE37065Down-0.5927870470
GSE28863_A1Up0.1862864035
GSE28863_A2Up0.0128066486
GSE28863_A3Up0.1019939180
GSE28863_A4Up0.0617603207
GSE48662Down-0.0046257308

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

22538858Cardiac expression of its bioinformatically predicted target mimecan (osteoglycin, OGN) was gradually decreased with advanced age
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