HCSGD entry for ATP4A

1. General information

Official gene symbolATP4A
Entrez ID495
Gene full nameATPase, H+/K+ exchanging, alpha polypeptide
Other gene symbolsATP6A
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000287Magnesium ion bindingIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006200ATP catabolic processTASbiological_process
GO:0006754ATP biosynthetic processIEAbiological_process
GO:0006810TransportTASbiological_process
GO:0008900Hydrogen:potassium-exchanging ATPase activityIEAmolecular_function
GO:0010155Regulation of proton transportIEAbiological_process
GO:0015991ATP hydrolysis coupled proton transportIEAbiological_process
GO:0034220Ion transmembrane transportTASbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0045851PH reductionIEAbiological_process
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0055085Transmembrane transportTASbiological_process
GO:0071805Potassium ion transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.60809264850.75767724250.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0511692682
GSE13712_SHEARUp0.3270849481
GSE13712_STATICUp0.0355687359
GSE19018Down-0.1664152518
GSE19899_A1Up0.0049432398
GSE19899_A2Up0.0375731855
PubMed_21979375_A1Down-0.1542514828
PubMed_21979375_A2Down-0.3568508735
GSE35957Down-0.0005809245
GSE36640Down-0.0336406091
GSE54402Up0.0773474663
GSE9593Down-0.0029357194
GSE43922Up0.0214473926
GSE24585Up0.0642794027
GSE37065Up0.0471284064
GSE28863_A1Up0.0573758176
GSE28863_A2Up0.0446915074
GSE28863_A3Up0.3295250260
GSE28863_A4Up0.0781148995
GSE48662Up0.1113770619

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

PantoprazoleDB00213 APRD00073
OmeprazoleDB00338 APRD00446
LansoprazoleDB00448 APRD00077
EsomeprazoleDB00736 APRD00363
RabeprazoleDB01129 APRD01212
TAK-390MRDB05351 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.