HCSGD entry for OAZ1
1. General information
| Official gene symbol | OAZ1 |
|---|---|
| Entrez ID | 4946 |
| Gene full name | ornithine decarboxylase antizyme 1 |
| Other gene symbols | AZI OAZ |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006521 | Regulation of cellular amino acid metabolic process | TAS | biological_process |
| GO:0006596 | Polyamine biosynthetic process | TAS | biological_process |
| GO:0008073 | Ornithine decarboxylase inhibitor activity | IEA | molecular_function |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0043086 | Negative regulation of catalytic activity | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0050790 | Regulation of catalytic activity | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5946227423 | 0.6665463318 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0630582969 |
| GSE13712_SHEAR | Up | 0.0410521322 |
| GSE13712_STATIC | Down | -0.0446000386 |
| GSE19018 | Up | 0.5998586496 |
| GSE19899_A1 | Down | -0.1166642665 |
| GSE19899_A2 | Up | 0.0539172935 |
| PubMed_21979375_A1 | Up | 0.2392237093 |
| PubMed_21979375_A2 | Down | -0.4646783205 |
| GSE35957 | Up | 0.1528750929 |
| GSE36640 | Up | 0.0683323525 |
| GSE54402 | Up | 0.1778959598 |
| GSE9593 | Up | 0.1392021614 |
| GSE43922 | Up | 0.0141577443 |
| GSE24585 | Down | -0.0025002235 |
| GSE37065 | Up | 0.0835037614 |
| GSE28863_A1 | Down | -0.1444082803 |
| GSE28863_A2 | Down | -0.2120354297 |
| GSE28863_A3 | Up | 0.0657145869 |
| GSE28863_A4 | Up | 0.0420550023 |
| GSE48662 | Down | -0.3034270963 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Ornithine | DB00129 | NUTR00043 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030185 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-320a | MIMAT0000510 | MIRT044721 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047539 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049825 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-29a-3p | MIMAT0000086 | MIRT049974 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
