HCSGD entry for GPX8
1. General information
| Official gene symbol | GPX8 |
|---|---|
| Entrez ID | 493869 |
| Gene full name | glutathione peroxidase 8 (putative) |
| Other gene symbols | EPLA847 GPx-8 GSHPx-8 UNQ847 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004602 | Glutathione peroxidase activity | IEA | molecular_function |
| GO:0006979 | Response to oxidative stress | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9601511645 | 0.0103566164 | 0.9999902473 | 0.2004386029 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2125003698 |
| GSE13712_SHEAR | Down | -0.0976943538 |
| GSE13712_STATIC | Down | -0.5597584271 |
| GSE19018 | Up | 0.2768690565 |
| GSE19899_A1 | Down | -1.3111510062 |
| GSE19899_A2 | Down | -0.7633299216 |
| PubMed_21979375_A1 | Down | -1.3179294426 |
| PubMed_21979375_A2 | Down | -1.3446559118 |
| GSE35957 | Down | -0.0403534101 |
| GSE36640 | Up | 0.3025372331 |
| GSE54402 | Down | -0.8228756422 |
| GSE9593 | Up | 0.2237990304 |
| GSE43922 | Down | -0.9434317267 |
| GSE24585 | Down | -0.0038760215 |
| GSE37065 | Down | -0.0241242853 |
| GSE28863_A1 | Up | 0.0588480404 |
| GSE28863_A2 | Up | 0.0045246028 |
| GSE28863_A3 | Down | -0.5869113057 |
| GSE28863_A4 | Down | -0.3131522260 |
| GSE48662 | Up | 0.0592652919 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Glutathione | DB00143 | NUTR00029 | EXPT01650 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-340-5p | MIMAT0004692 | MIRT019577 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
