HCSGD entry for GPR143
1. General information
| Official gene symbol | GPR143 |
|---|---|
| Entrez ID | 4935 |
| Gene full name | G protein-coupled receptor 143 |
| Other gene symbols | NYS6 OA1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004930 | G-protein coupled receptor activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005765 | Lysosomal membrane | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006726 | Eye pigment biosynthetic process | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | IDA IMP | biological_process |
| GO:0007218 | Neuropeptide signaling pathway | IDA | biological_process |
| GO:0007268 | Synaptic transmission | IDA | biological_process |
| GO:0007601 | Visual perception | TAS | biological_process |
| GO:0016020 | Membrane | IEA TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016324 | Apical plasma membrane | IDA | cellular_component |
| GO:0032400 | Melanosome localization | IDA ISS | biological_process |
| GO:0032402 | Melanosome transport | IDA IEA | biological_process |
| GO:0032438 | Melanosome organization | IMP | biological_process |
| GO:0033162 | Melanosome membrane | IDA | cellular_component |
| GO:0035240 | Dopamine binding | IDA | molecular_function |
| GO:0035584 | Calcium-mediated signaling using intracellular calcium source | IDA | biological_process |
| GO:0035643 | L-DOPA receptor activity | IDA | molecular_function |
| GO:0042470 | Melanosome | IDA | cellular_component |
| GO:0048015 | Phosphatidylinositol-mediated signaling | IDA | biological_process |
| GO:0050848 | Regulation of calcium-mediated signaling | IDA | biological_process |
| GO:0072544 | L-DOPA binding | IDA | molecular_function |
| GO:0072545 | Tyrosine binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0416024923 | 0.9510445766 | 0.4572105219 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1068571620 |
| GSE13712_SHEAR | Up | 2.7774753093 |
| GSE13712_STATIC | Up | 2.7672478955 |
| GSE19018 | Up | 0.0278639724 |
| GSE19899_A1 | Up | 0.1744067381 |
| GSE19899_A2 | Up | 0.2819334237 |
| PubMed_21979375_A1 | Up | 0.1537684452 |
| PubMed_21979375_A2 | Up | 0.2743255375 |
| GSE35957 | Down | -0.2178917140 |
| GSE36640 | Up | 0.0823244853 |
| GSE54402 | Down | -0.0126800363 |
| GSE9593 | Up | 0.0316364788 |
| GSE43922 | Up | 0.0329378314 |
| GSE24585 | Up | 0.0960262775 |
| GSE37065 | Up | 0.0398241320 |
| GSE28863_A1 | Down | -0.0518751803 |
| GSE28863_A2 | Down | -0.0403238941 |
| GSE28863_A3 | Up | 0.2434450651 |
| GSE28863_A4 | Down | -0.0226367175 |
| GSE48662 | Down | -0.0259478566 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019367 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
