HCSGD entry for ROR1
1. General information
| Official gene symbol | ROR1 |
|---|---|
| Entrez ID | 4919 |
| Gene full name | receptor tyrosine kinase-like orphan receptor 1 |
| Other gene symbols | NTRKR1 dJ537F10.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004714 | Transmembrane receptor protein tyrosine kinase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007169 | Transmembrane receptor protein tyrosine kinase signaling pathway | IEA | biological_process |
| GO:0017147 | Wnt-protein binding | IPI | molecular_function |
| GO:0018108 | Peptidyl-tyrosine phosphorylation | TAS | biological_process |
| GO:0043235 | Receptor complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4016649481 | 0.0036970290 | 0.9999902473 | 0.1236288608 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4865966355 |
| GSE13712_SHEAR | Up | 0.7309746022 |
| GSE13712_STATIC | Up | 0.7782297353 |
| GSE19018 | Down | -0.9595845172 |
| GSE19899_A1 | Down | -0.6849429571 |
| GSE19899_A2 | Down | -2.3385546907 |
| PubMed_21979375_A1 | Down | -0.8343318391 |
| PubMed_21979375_A2 | Down | -1.3869345982 |
| GSE35957 | Up | 1.1753599440 |
| GSE36640 | Down | -0.3107147334 |
| GSE54402 | Down | -0.7420102132 |
| GSE9593 | Up | 0.2177300489 |
| GSE43922 | Down | -1.4185654624 |
| GSE24585 | Down | -0.2753716222 |
| GSE37065 | Down | -0.8879203807 |
| GSE28863_A1 | Up | 0.0918939155 |
| GSE28863_A2 | Up | 0.5875722657 |
| GSE28863_A3 | Down | -0.1453199463 |
| GSE28863_A4 | Up | 0.2311505472 |
| GSE48662 | Down | -0.0920159207 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022495 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025759 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027572 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031179 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
