HCSGD entry for ATP2B1
1. General information
| Official gene symbol | ATP2B1 |
|---|---|
| Entrez ID | 490 |
| Gene full name | ATPase, Ca++ transporting, plasma membrane 1 |
| Other gene symbols | PMCA1 PMCA1kb |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005388 | Calcium-transporting ATPase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005516 | Calmodulin binding | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006200 | ATP catabolic process | TAS | biological_process |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0046182402 | 0.2246949280 | 0.1787598529 | 0.9118785538 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.8491079908 |
| GSE13712_SHEAR | Down | -0.9831171209 |
| GSE13712_STATIC | Down | -0.9681663404 |
| GSE19018 | Down | -1.0229419214 |
| GSE19899_A1 | Up | 0.2951515545 |
| GSE19899_A2 | Up | 1.3421057805 |
| PubMed_21979375_A1 | Up | 1.9717513373 |
| PubMed_21979375_A2 | Up | 1.3389122053 |
| GSE35957 | Up | 0.3131447468 |
| GSE36640 | Down | -1.5092446219 |
| GSE54402 | Up | 0.3860310891 |
| GSE9593 | Up | 0.0209587891 |
| GSE43922 | Up | 0.9361574272 |
| GSE24585 | Up | 0.3142885977 |
| GSE37065 | Up | 0.2261425870 |
| GSE28863_A1 | Down | -0.0041232894 |
| GSE28863_A2 | Up | 0.8067674536 |
| GSE28863_A3 | Down | -0.5579219647 |
| GSE28863_A4 | Up | 0.4508581132 |
| GSE48662 | Up | 0.2508891456 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-204-5p | MIMAT0000265 | MIRT005818 | Microarray | Functional MTI (Weak) | 21282569 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039645 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052579 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-204-5p | MIMAT0000265 | NA | hsa-miR-204 | 20369013 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
