HCSGD entry for NPAT
1. General information
| Official gene symbol | NPAT |
|---|---|
| Entrez ID | 4863 |
| Gene full name | nuclear protein, ataxia-telangiectasia locus |
| Other gene symbols | E14 E14/NPAT p220 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000083 | Regulation of transcription involved in G1/S transition of mitotic cell cycle | IMP | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IDA | molecular_function |
| GO:0003713 | Transcription coactivator activity | IDA IMP | molecular_function |
| GO:0003714 | Transcription corepressor activity | IMP | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0008022 | Protein C-terminus binding | IPI | molecular_function |
| GO:0010468 | Regulation of gene expression | IMP | biological_process |
| GO:0015030 | Cajal body | IDA | cellular_component |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0047485 | Protein N-terminus binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6716010334 | 0.2487277649 | 0.9999902473 | 0.9587351296 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2153032783 |
| GSE13712_SHEAR | Down | -0.0386475381 |
| GSE13712_STATIC | Down | -0.1672473348 |
| GSE19018 | Up | 0.1744279392 |
| GSE19899_A1 | Up | 0.0149870327 |
| GSE19899_A2 | Down | -0.3641925724 |
| PubMed_21979375_A1 | Up | 0.2193656032 |
| PubMed_21979375_A2 | Down | -0.0199833527 |
| GSE35957 | Down | -0.0687130473 |
| GSE36640 | Down | -0.9364897992 |
| GSE54402 | Up | 0.2108418119 |
| GSE9593 | Down | -0.0315967932 |
| GSE43922 | Down | -0.0331804200 |
| GSE24585 | Up | 0.3036678407 |
| GSE37065 | Up | 0.3307935943 |
| GSE28863_A1 | Down | -0.1763401964 |
| GSE28863_A2 | Up | 0.1211987463 |
| GSE28863_A3 | Down | -0.5502770945 |
| GSE28863_A4 | Up | 0.0728594749 |
| GSE48662 | Down | -0.5350235468 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-17-5p | MIMAT0000070 | MIRT000261 | Luciferase reporter assay | Functional MTI | 19734348 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
