HCSGD entry for NNMT
1. General information
| Official gene symbol | NNMT |
|---|---|
| Entrez ID | 4837 |
| Gene full name | nicotinamide N-methyltransferase |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0008112 | Nicotinamide N-methyltransferase activity | IEA | molecular_function |
| GO:0008168 | Methyltransferase activity | IEA | molecular_function |
| GO:0010243 | Response to organonitrogen compound | IEA | biological_process |
| GO:0031100 | Organ regeneration | IEA | biological_process |
| GO:0032259 | Methylation | TAS | biological_process |
| GO:0042493 | Response to drug | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9884864329 | 0.0007355952 | 0.9999902473 | 0.0512818421 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.4929365736 |
| GSE13712_SHEAR | Up | 0.0804538390 |
| GSE13712_STATIC | Up | 0.1841379567 |
| GSE19018 | Down | -0.7818217808 |
| GSE19899_A1 | Down | -1.2614648626 |
| GSE19899_A2 | Down | -1.4175578463 |
| PubMed_21979375_A1 | Down | -1.5456501274 |
| PubMed_21979375_A2 | Down | -2.0585973692 |
| GSE35957 | Up | 0.4599029904 |
| GSE36640 | Down | -1.2814238394 |
| GSE54402 | Down | -2.7689850397 |
| GSE9593 | Up | 0.0169440917 |
| GSE43922 | Down | -0.3800751491 |
| GSE24585 | Down | -0.1014652485 |
| GSE37065 | Down | -0.2268224531 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.0721961245 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022959 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027710 | Microarray | Functional MTI (Weak) | 19088304 |
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