HCSGD entry for NMT1
1. General information
| Official gene symbol | NMT1 |
|---|---|
| Entrez ID | 4836 |
| Gene full name | N-myristoyltransferase 1 |
| Other gene symbols | NMT |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001701 | In utero embryonic development | IEA | biological_process |
| GO:0003824 | Catalytic activity | TAS | molecular_function |
| GO:0004379 | Glycylpeptide N-tetradecanoyltransferase activity | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006499 | N-terminal protein myristoylation | IEA | biological_process |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0007603 | Phototransduction, visible light | TAS | biological_process |
| GO:0009249 | Protein lipoylation | TAS | biological_process |
| GO:0015629 | Actin cytoskeleton | IDA | cellular_component |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0016056 | Rhodopsin mediated signaling pathway | TAS | biological_process |
| GO:0022400 | Regulation of rhodopsin mediated signaling pathway | TAS | biological_process |
| GO:0030054 | Cell junction | IDA | cellular_component |
| GO:0097193 | Intrinsic apoptotic signaling pathway | TAS | biological_process |
| GO:1900740 | Positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0576587668 | 0.9755117625 | 0.5208685293 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2840690875 |
| GSE13712_SHEAR | Down | -0.1573796526 |
| GSE13712_STATIC | Up | 0.1057673717 |
| GSE19018 | Up | 0.2309654842 |
| GSE19899_A1 | Up | 0.0746761736 |
| GSE19899_A2 | Up | 0.1989777786 |
| PubMed_21979375_A1 | Up | 0.4205537131 |
| PubMed_21979375_A2 | Up | 0.1341953128 |
| GSE35957 | Down | -0.1806096723 |
| GSE36640 | Up | 0.3268391717 |
| GSE54402 | Up | 0.0938433110 |
| GSE9593 | Up | 0.2617496368 |
| GSE43922 | Down | -0.0226548131 |
| GSE24585 | Up | 0.2448897742 |
| GSE37065 | Up | 0.1124715755 |
| GSE28863_A1 | Up | 0.6319991606 |
| GSE28863_A2 | Up | 0.3785496354 |
| GSE28863_A3 | Down | -0.2689268181 |
| GSE28863_A4 | Up | 0.2067301061 |
| GSE48662 | Up | 0.3127053965 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| (1-Methyl-1h-Imidazol-2-Yl)-(3-Methyl-4-{3-[(Pyridin-3-Ylmethyl)-Amino]-Propoxy}-Benzofuran-2-Yl)-Methanone | DB03062 | EXPT02748 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-744-5p | MIMAT0004945 | MIRT037569 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039990 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041243 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045083 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046372 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30d-5p | MIMAT0000245 | MIRT047822 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
