HCSGD entry for NQO2
1. General information
| Official gene symbol | NQO2 |
|---|---|
| Entrez ID | 4835 |
| Gene full name | NAD(P)H dehydrogenase, quinone 2 |
| Other gene symbols | DHQV DIA6 NMOR2 QR2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001512 | Dihydronicotinamide riboside quinone reductase activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0007613 | Memory | IEA | biological_process |
| GO:0008753 | NADPH dehydrogenase (quinone) activity | TAS | molecular_function |
| GO:0009055 | Electron carrier activity | TAS | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6710411952 | 0.0464679533 | 0.9999902473 | 0.4043249587 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0042134944 |
| GSE13712_SHEAR | Down | -0.4190779869 |
| GSE13712_STATIC | Down | -0.1872240621 |
| GSE19018 | Up | 0.0492863763 |
| GSE19899_A1 | Down | -1.0610480206 |
| GSE19899_A2 | Down | -0.9722354126 |
| PubMed_21979375_A1 | Down | -0.0786421467 |
| PubMed_21979375_A2 | Down | -1.2399778467 |
| GSE35957 | Down | -0.3802130635 |
| GSE36640 | Up | 0.0728735761 |
| GSE54402 | Down | -0.0840436481 |
| GSE9593 | Down | -0.0547917846 |
| GSE43922 | Down | -1.1537405678 |
| GSE24585 | Up | 0.6942724567 |
| GSE37065 | Up | 0.3145738863 |
| GSE28863_A1 | Up | 0.0659594038 |
| GSE28863_A2 | Up | 0.3307800027 |
| GSE28863_A3 | Down | -0.0551881098 |
| GSE28863_A4 | Up | 0.1714723679 |
| GSE48662 | Up | 0.1023261773 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
| Menadione | DB00170 | NUTR00062 |
| Melatonin | DB01065 | APRD00742 | DB08189 |
| Primaquine | DB01087 | APRD00604 |
| 10-Propargyl-5,8-Dideazafolic Acid | DB03541 | EXPT00839 |
| CB1954 | DB04253 | EXPT00837 |
| (3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione | DB07339 | - |
| N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide | DB08190 | - |
| 5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one | DB08228 | - |
| 6-methoxy-9-methyl[1,3]dioxolo[4,5-h]quinolin-8(9H)-one | DB08744 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-320a | MIMAT0000510 | MIRT044829 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
