HCSGD entry for NIT1
1. General information
| Official gene symbol | NIT1 |
|---|---|
| Entrez ID | 4817 |
| Gene full name | nitrilase 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000257 | Nitrilase activity | TAS | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0006807 | Nitrogen compound metabolic process | IEA | biological_process |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0016810 | Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0256551879 | 0.9529142814 | 0.3754387437 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2157437931 |
| GSE13712_SHEAR | Down | -0.0179997389 |
| GSE13712_STATIC | Up | 0.0426909873 |
| GSE19018 | Up | 0.1686580037 |
| GSE19899_A1 | Up | 0.5096167664 |
| GSE19899_A2 | Up | 0.6399952681 |
| PubMed_21979375_A1 | Up | 1.5336817652 |
| PubMed_21979375_A2 | Up | 0.4588709917 |
| GSE35957 | Down | -0.2283486316 |
| GSE36640 | Up | 0.2642997513 |
| GSE54402 | Up | 0.0482660751 |
| GSE9593 | Down | -0.0250326798 |
| GSE43922 | Up | 0.2519820267 |
| GSE24585 | Up | 0.6889577375 |
| GSE37065 | Down | -0.0126734244 |
| GSE28863_A1 | Up | 0.2415664209 |
| GSE28863_A2 | Up | 0.0677805029 |
| GSE28863_A3 | Down | -0.3409211366 |
| GSE28863_A4 | Down | -0.3477357125 |
| GSE48662 | Up | 0.4827193309 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-224-5p | MIMAT0000281 | MIRT003233 | Luciferase reporter assay | Non-Functional MTI | 20065103 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
