HCSGD entry for NFYC
1. General information
| Official gene symbol | NFYC |
|---|---|
| Entrez ID | 4802 |
| Gene full name | nuclear transcription factor Y, gamma |
| Other gene symbols | CBF-C CBFC H1TF2A HAP5 HSM NF-YC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IDA IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0003713 | Transcription coactivator activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006457 | Protein folding | TAS | biological_process |
| GO:0016602 | CCAAT-binding factor complex | IDA IEA | cellular_component |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0046982 | Protein heterodimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9052932639 | 0.4292582539 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0065166249 |
| GSE13712_SHEAR | Up | 0.0335819351 |
| GSE13712_STATIC | Down | -0.1007953575 |
| GSE19018 | Down | -0.0655157806 |
| GSE19899_A1 | Down | -0.1404070520 |
| GSE19899_A2 | Up | 0.1980476367 |
| PubMed_21979375_A1 | Up | 0.5777748841 |
| PubMed_21979375_A2 | Down | -0.1162903143 |
| GSE35957 | Down | -0.2896383056 |
| GSE36640 | Down | -0.3790748817 |
| GSE54402 | Up | 0.0467756603 |
| GSE9593 | Down | -0.1186600407 |
| GSE43922 | Down | -0.0592652813 |
| GSE24585 | Up | 0.1555469937 |
| GSE37065 | Up | 0.0870641551 |
| GSE28863_A1 | Up | 0.0176822517 |
| GSE28863_A2 | Up | 0.0574482281 |
| GSE28863_A3 | Down | -0.3394624158 |
| GSE28863_A4 | Down | -0.0965059212 |
| GSE48662 | Up | 0.0113853200 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-33a-5p | MIMAT0000091 | MIRT007356 | Immunofluorescence//Luciferase reporter assay//Western blot | Functional MTI | 23547260 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020636 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046926 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
