HCSGD entry for NFIL3


1. General information

Official gene symbolNFIL3
Entrez ID4783
Gene full namenuclear factor, interleukin 3 regulated
Other gene symbolsE4BP4 IL3BP1 NF-IL3A NFIL3A
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIMPbiological_process
GO:0000977RNA polymerase II regulatory region sequence-specific DNA bindingIDAmolecular_function
GO:0000979RNA polymerase II core promoter sequence-specific DNA bindingIEAmolecular_function
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcriptionIDAmolecular_function
GO:0003677DNA bindingTASmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0003714Transcription corepressor activityTASmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0006955Immune responseTASbiological_process
GO:0007623Circadian rhythmIEAbiological_process
GO:0010628Positive regulation of gene expressionIEAbiological_process
GO:0071353Cellular response to interleukin-4IEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07704507430.01805439000.58609924860.2629826231

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3355406077
GSE13712_SHEARUp0.2036981291
GSE13712_STATICDown-0.3867198476
GSE19018Up1.5664314272
GSE19899_A1Down-1.4438240892
GSE19899_A2Up0.1368429787
PubMed_21979375_A1Down-0.8075664752
PubMed_21979375_A2Down-0.4032319934
GSE35957Up0.7524659411
GSE36640Down-2.2034512230
GSE54402Down-0.6170386083
GSE9593Down-0.3454664667
GSE43922Down-0.6438241193
GSE24585Up0.2616057949
GSE37065Up0.6176625552
GSE28863_A1Up0.7414339098
GSE28863_A2Up0.4975991556
GSE28863_A3Down-0.0105797110
GSE28863_A4Down-0.1833273199
GSE48662Up0.1779111931

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018550MicroarrayFunctional MTI (Weak)18185580
hsa-miR-98-5pMIMAT0000096MIRT027704MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.