HCSGD entry for NFATC3
1. General information
| Official gene symbol | NFATC3 |
|---|---|
| Entrez ID | 4775 |
| Gene full name | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| Other gene symbols | NFAT4 NFATX |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001569 | Patterning of blood vessels | IEA | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006954 | Inflammatory response | TAS | biological_process |
| GO:0007507 | Heart development | IEA | biological_process |
| GO:0038095 | Fc-epsilon receptor signaling pathway | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0045333 | Cellular respiration | IEA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0051145 | Smooth muscle cell differentiation | IEA | biological_process |
| GO:0055001 | Muscle cell development | IEA | biological_process |
| GO:0071285 | Cellular response to lithium ion | IEA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1275503172 | 0.9222381406 | 0.7269485170 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2354273746 |
| GSE13712_SHEAR | Down | -0.1596108118 |
| GSE13712_STATIC | Down | -0.0410450134 |
| GSE19018 | Up | 0.0178842343 |
| GSE19899_A1 | Up | 0.1027775485 |
| GSE19899_A2 | Up | 0.1948180142 |
| PubMed_21979375_A1 | Up | 0.6688302399 |
| PubMed_21979375_A2 | Up | 0.6108825740 |
| GSE35957 | Down | -0.2674784463 |
| GSE36640 | Down | -0.3616790738 |
| GSE54402 | Up | 0.2800321498 |
| GSE9593 | Down | -0.1440785546 |
| GSE43922 | Up | 0.2544169830 |
| GSE24585 | Up | 0.0292922843 |
| GSE37065 | Up | 0.0639814500 |
| GSE28863_A1 | Up | 0.5114506732 |
| GSE28863_A2 | Up | 0.2699761042 |
| GSE28863_A3 | Down | -0.3953639979 |
| GSE28863_A4 | Up | 0.0865845405 |
| GSE48662 | Up | 0.0826648684 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-9-5p | MIMAT0000441 | MIRT021368 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-361-3p | MIMAT0004682 | MIRT038275 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042979 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052288 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
