HCSGD entry for NEUROG1


1. General information

Official gene symbolNEUROG1
Entrez ID4762
Gene full nameneurogenin 1
Other gene symbolsAKA Math4C NEUROD3 bHLHa6 ngn1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000989Transcription factor binding transcription factor activityISSmolecular_function
GO:0003677DNA bindingISSmolecular_function
GO:0003682Chromatin bindingISSmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0030182Neuron differentiationIEAbiological_process
GO:0031536Positive regulation of exit from mitosisIEAbiological_process
GO:0042472Inner ear morphogenesisIEAbiological_process
GO:0043204PerikaryonIEAcellular_component
GO:0045165Cell fate commitmentIEAbiological_process
GO:0045666Positive regulation of neuron differentiationISSbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterISSbiological_process
GO:0046983Protein dimerization activityIEAmolecular_function
GO:0051091Positive regulation of sequence-specific DNA binding transcription factor activityISSbiological_process
GO:0070888E-box bindingISSmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.54874960300.64107534290.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0522612984
GSE13712_SHEARDown-0.0241547610
GSE13712_STATICUp0.1339842182
GSE19018Down-0.0316700755
GSE19899_A1Up0.0113781227
GSE19899_A2Up0.2097868730
PubMed_21979375_A1Down-0.1759664994
PubMed_21979375_A2Down-0.2138863156
GSE35957Down-0.0320814840
GSE36640Down-0.0469908782
GSE54402Up0.0249023555
GSE9593Down-0.4170991151
GSE43922Up0.2067438180
GSE24585Up0.2484217867
GSE37065Down-0.1038688761
GSE28863_A1Down-0.1106493302
GSE28863_A2Up0.3377846765
GSE28863_A3Up0.3141117420
GSE28863_A4Up0.0028060585
GSE48662Down-0.0119519875

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017336MicroarrayFunctional MTI (Weak)18185580
hsa-miR-155-5pMIMAT0000646MIRT021004ProteomicsFunctional MTI (Weak)18668040
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.