HCSGD entry for NEFM
1. General information
| Official gene symbol | NEFM |
|---|---|
| Entrez ID | 4741 |
| Gene full name | neurofilament, medium polypeptide |
| Other gene symbols | NEF3 NF-M NFM |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000226 | Microtubule cytoskeleton organization | IEA | biological_process |
| GO:0005198 | Structural molecule activity | IEA | molecular_function |
| GO:0005200 | Structural constituent of cytoskeleton | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005882 | Intermediate filament | IEA | cellular_component |
| GO:0005883 | Neurofilament | IEA | cellular_component |
| GO:0008088 | Axon cargo transport | IEA | biological_process |
| GO:0030424 | Axon | TAS | cellular_component |
| GO:0031133 | Regulation of axon diameter | IEA | biological_process |
| GO:0031594 | Neuromuscular junction | IEA | cellular_component |
| GO:0045110 | Intermediate filament bundle assembly | IEA | biological_process |
| GO:0060052 | Neurofilament cytoskeleton organization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0026544204 | 0.9696752251 | 0.1391505929 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.2161077580 |
| GSE13712_SHEAR | Down | -0.2704003973 |
| GSE13712_STATIC | Up | 0.0101768960 |
| GSE19018 | Up | 0.0909075532 |
| GSE19899_A1 | Up | 0.0654582211 |
| GSE19899_A2 | Up | 0.3110672867 |
| PubMed_21979375_A1 | Up | 1.9038437720 |
| PubMed_21979375_A2 | Up | 1.3299500707 |
| GSE35957 | Up | 0.3981662426 |
| GSE36640 | Up | 0.0993095090 |
| GSE54402 | Up | 1.2747871799 |
| GSE9593 | Down | -0.1258839118 |
| GSE43922 | Up | 1.0870771269 |
| GSE24585 | Up | 0.5263400297 |
| GSE37065 | Up | 0.2666926370 |
| GSE28863_A1 | Down | -0.1144159431 |
| GSE28863_A2 | Up | 0.0166922069 |
| GSE28863_A3 | Up | 0.9080657361 |
| GSE28863_A4 | Up | 0.0658201856 |
| GSE48662 | Down | -0.3251786525 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7a-5p | MIMAT0000062 | MIRT004961 | qRT-PCR | Functional MTI (Weak) | 17942906 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT016901 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
