HCSGD entry for SEPT2
1. General information
| Official gene symbol | SEPT2 |
|---|---|
| Entrez ID | 4735 |
| Gene full name | septin 2 |
| Other gene symbols | DIFF6 NEDD5 Pnutl3 hNedd5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000145 | Exocyst | IEA | cellular_component |
| GO:0000777 | Condensed chromosome kinetochore | IEA | cellular_component |
| GO:0002036 | Regulation of L-glutamate transport | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005819 | Spindle | IEA | cellular_component |
| GO:0005938 | Cell cortex | ISS | cellular_component |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0007224 | Smoothened signaling pathway | IEA ISS | biological_process |
| GO:0009986 | Cell surface | IEA | cellular_component |
| GO:0015629 | Actin cytoskeleton | IDA | cellular_component |
| GO:0030234 | Enzyme regulator activity | IEA | molecular_function |
| GO:0030496 | Midbody | IEA | cellular_component |
| GO:0031105 | Septin complex | IEA | cellular_component |
| GO:0031175 | Neuron projection development | IEA | biological_process |
| GO:0032154 | Cleavage furrow | IEA | cellular_component |
| GO:0032880 | Regulation of protein localization | IEA | biological_process |
| GO:0032947 | Protein complex scaffold | IEA | molecular_function |
| GO:0042384 | Cilium assembly | IEA ISS | biological_process |
| GO:0045202 | Synapse | IEA | cellular_component |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0060170 | Ciliary membrane | IEA ISS | cellular_component |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9576507010 | 0.2343216823 | 0.9999902473 | 0.9323511941 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0470483203 |
| GSE13712_SHEAR | Down | -0.1639978361 |
| GSE13712_STATIC | Down | -0.2057015211 |
| GSE19018 | Up | 0.0798004413 |
| GSE19899_A1 | Down | -0.1350233341 |
| GSE19899_A2 | Down | -0.0920712926 |
| PubMed_21979375_A1 | Down | -0.5949243720 |
| PubMed_21979375_A2 | Down | -0.1112949325 |
| GSE35957 | Down | -0.1003839924 |
| GSE36640 | Down | -0.0253667525 |
| GSE54402 | Down | -0.0857608662 |
| GSE9593 | Up | 0.0001245183 |
| GSE43922 | Down | -0.0281139578 |
| GSE24585 | Up | 0.1269079001 |
| GSE37065 | Down | -0.0913261744 |
| GSE28863_A1 | Up | 0.0756212634 |
| GSE28863_A2 | Up | 0.2243669641 |
| GSE28863_A3 | Down | -0.4346682788 |
| GSE28863_A4 | Down | -0.0100548676 |
| GSE48662 | Down | -0.1183685807 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | MIRT004515 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022377 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036930 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037693 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-421 | MIMAT0003339 | MIRT039399 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-652-3p | MIMAT0003322 | MIRT039504 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040241 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046451 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106a-5p | MIMAT0000103 | MIRT048333 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23a-3p | MIMAT0000078 | MIRT050437 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050517 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050919 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | NA | hsa-miR-373 | 15685193 |
Entries Per Page
Displaying Page of
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
