HCSGD entry for NDUFS3

1. General information

Official gene symbolNDUFS3
Entrez ID4722
Gene full nameNADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
Other gene symbolsCI-30
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003954NADH dehydrogenase activityIMPmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005739MitochondrionNAScellular_component
GO:0005743Mitochondrial inner membraneTAScellular_component
GO:0005747Mitochondrial respiratory chain complex IIDA NAScellular_component
GO:0006120Mitochondrial electron transport, NADH to ubiquinoneNASbiological_process
GO:0008137NADH dehydrogenase (ubiquinone) activityNASmolecular_function
GO:0009055Electron carrier activityNASmolecular_function
GO:0022904Respiratory electron transport chainTASbiological_process
GO:0030308Negative regulation of cell growthIMPbiological_process
GO:0031966Mitochondrial membraneIDAcellular_component
GO:0044237Cellular metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0072593Reactive oxygen species metabolic processIMPbiological_process
GO:2001243Negative regulation of intrinsic apoptotic signaling pathwayIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.30162844500.54896142240.99969783481.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.9013722523
GSE13712_SHEARDown-0.2850483693
GSE13712_STATICDown-0.1099595498
GSE19018Down-0.2301948063
GSE19899_A1Up0.2781958181
GSE19899_A2Up0.2193995388
PubMed_21979375_A1Up0.4414628965
PubMed_21979375_A2Up0.1085253014
GSE35957Down-0.4954793007
GSE36640Down-0.1006205591
GSE54402Up0.3121324953
GSE9593Down-0.3391844806
GSE43922Up0.2068669690
GSE24585Up0.0460497581
GSE37065Down-0.0313189113
GSE28863_A1Down-0.3208439489
GSE28863_A2Down-0.0507131219
GSE28863_A3Down-0.1189084478
GSE28863_A4Up0.1676577912
GSE48662Down-0.1166101469

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.