HCSGD entry for NDUFAB1

1. General information

Official gene symbolNDUFAB1
Entrez ID4706
Gene full nameNADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
Other gene symbolsACP FASN2A SDAP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000036ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic processNASmolecular_function
GO:0005504Fatty acid bindingISSmolecular_function
GO:0005509Calcium ion bindingNASmolecular_function
GO:0005739MitochondrionIEAcellular_component
GO:0005743Mitochondrial inner membraneTAScellular_component
GO:0005747Mitochondrial respiratory chain complex IIDA ISS NAScellular_component
GO:0005759Mitochondrial matrixISScellular_component
GO:0006120Mitochondrial electron transport, NADH to ubiquinoneNASbiological_process
GO:0006633Fatty acid biosynthetic processIEA NASbiological_process
GO:0008137NADH dehydrogenase (ubiquinone) activityNASmolecular_function
GO:0009249Protein lipoylationIMPbiological_process
GO:0022904Respiratory electron transport chainTASbiological_process
GO:0031966Mitochondrial membraneISS NAScellular_component
GO:0044237Cellular metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.14165773340.80028314650.75610612201.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4274015309
GSE13712_SHEARDown-0.1291443926
GSE13712_STATICUp0.0149417569
GSE19018Up0.2160636797
GSE19899_A1Up0.2419707290
GSE19899_A2Up0.4015778895
PubMed_21979375_A1Up0.6102536828
PubMed_21979375_A2Up0.2616936876
GSE35957Down-0.3423230701
GSE36640Up0.0825199018
GSE54402Up0.4103486439
GSE9593Down-0.2450223430
GSE43922Up0.0879265879
GSE24585Down-0.5906019166
GSE37065Up0.1299109030
GSE28863_A1Down-0.0375078204
GSE28863_A2Down-0.0017808767
GSE28863_A3Down-0.3551696046
GSE28863_A4Up0.2236308157
GSE48662Up0.0275125430

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-615-3pMIMAT0003283MIRT040100CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.