HCSGD entry for NDUFA3
1. General information
| Official gene symbol | NDUFA3 |
|---|---|
| Entrez ID | 4696 |
| Gene full name | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa |
| Other gene symbols | B9 CI-B9 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005743 | Mitochondrial inner membrane | TAS | cellular_component |
| GO:0005747 | Mitochondrial respiratory chain complex I | IDA IEA NAS | cellular_component |
| GO:0006120 | Mitochondrial electron transport, NADH to ubiquinone | NAS | biological_process |
| GO:0008137 | NADH dehydrogenase (ubiquinone) activity | NAS | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0022904 | Respiratory electron transport chain | TAS | biological_process |
| GO:0044237 | Cellular metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0756126249 | 0.6410776452 | 0.5822052570 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3184371079 |
| GSE13712_SHEAR | Down | -0.3411726199 |
| GSE13712_STATIC | Down | -0.3279812505 |
| GSE19018 | Down | -0.0582573967 |
| GSE19899_A1 | Up | 0.3507844254 |
| GSE19899_A2 | Up | 0.8048663965 |
| PubMed_21979375_A1 | Up | 1.6073616506 |
| PubMed_21979375_A2 | Up | 0.6828761389 |
| GSE35957 | Down | -0.5409869457 |
| GSE36640 | Up | 0.3541700677 |
| GSE54402 | Up | 0.1701177991 |
| GSE9593 | Down | -0.1151128290 |
| GSE43922 | Up | 0.3603833904 |
| GSE24585 | Down | -0.1813573785 |
| GSE37065 | Down | -0.1070091490 |
| GSE28863_A1 | Down | -0.2209372624 |
| GSE28863_A2 | Down | -0.2331758481 |
| GSE28863_A3 | Up | 0.4251974825 |
| GSE28863_A4 | Down | -0.0057672824 |
| GSE48662 | Up | 0.0736350471 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-671-5p | MIMAT0003880 | MIRT039275 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044766 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051531 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 18977241 | Telomere lengths were calculated for 190 (82 men, 108 women) participants aged 79 years and associations with 384 SNPs, from 141 oxidative stress genes, identified 9 significant SNPS, of which those from 5 genes (GSTZ1, MSRA, NDUFA3, NDUFA8, VIM) had robust associations with physical aging biomarkers, respiratory function or grip strength |
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