HCSGD entry for NCF2
1. General information
Official gene symbol | NCF2 |
---|---|
Entrez ID | 4688 |
Gene full name | neutrophil cytosolic factor 2 |
Other gene symbols | NCF-2 NOXA2 P67-PHOX P67PHOX |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network

This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0001669 | Acrosomal vesicle | IEA | cellular_component |
GO:0002474 | Antigen processing and presentation of peptide antigen via MHC class I | TAS | biological_process |
GO:0002479 | Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | TAS | biological_process |
GO:0005515 | Protein binding | IPI | molecular_function |
GO:0005730 | Nucleolus | IDA | cellular_component |
GO:0005737 | Cytoplasm | IDA | cellular_component |
GO:0005829 | Cytosol | TAS | cellular_component |
GO:0006801 | Superoxide metabolic process | TAS | biological_process |
GO:0006968 | Cellular defense response | TAS | biological_process |
GO:0007568 | Aging | IEA | biological_process |
GO:0008022 | Protein C-terminus binding | IPI | molecular_function |
GO:0009055 | Electron carrier activity | TAS | molecular_function |
GO:0009749 | Response to glucose | IEA | biological_process |
GO:0014823 | Response to activity | IEA | biological_process |
GO:0016020 | Membrane | IEA | cellular_component |
GO:0032010 | Phagolysosome | TAS | cellular_component |
GO:0032496 | Response to lipopolysaccharide | IEA | biological_process |
GO:0032570 | Response to progesterone | IEA | biological_process |
GO:0032870 | Cellular response to hormone stimulus | IEA | biological_process |
GO:0034616 | Response to laminar fluid shear stress | IEA | biological_process |
GO:0042493 | Response to drug | IEA | biological_process |
GO:0042554 | Superoxide anion generation | IEA TAS | biological_process |
GO:0042590 | Antigen processing and presentation of exogenous peptide antigen via MHC class I | TAS | biological_process |
GO:0043020 | NADPH oxidase complex | TAS | cellular_component |
GO:0043525 | Positive regulation of neuron apoptotic process | IEA | biological_process |
GO:0045087 | Innate immune response | TAS | biological_process |
GO:0045730 | Respiratory burst | TAS | biological_process |
GO:0045777 | Positive regulation of blood pressure | IEA | biological_process |
GO:0048365 | Rac GTPase binding | IEA | molecular_function |
GO:0051701 | Interaction with host | TAS | biological_process |
GO:0055093 | Response to hyperoxia | IEA | biological_process |
GO:0090382 | Phagosome maturation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.2221019300 | 0.1588653091 | 0.9034505325 | 0.7700200920 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Up | 0.1086952832 |
GSE13712_SHEAR | Up | 0.3027111848 |
GSE13712_STATIC | Up | 0.0217636174 |
GSE19018 | Down | -0.0223128923 |
GSE19899_A1 | Down | -0.1753959902 |
GSE19899_A2 | Up | 0.5374703973 |
PubMed_21979375_A1 | Up | 0.1912768919 |
PubMed_21979375_A2 | Down | -0.2023727026 |
GSE35957 | Down | -0.0814782539 |
GSE36640 | Up | 1.6719457822 |
GSE54402 | Down | -0.3490201575 |
GSE9593 | Up | 0.1884742292 |
GSE43922 | Up | 0.0397520532 |
GSE24585 | Down | -0.1057628379 |
GSE37065 | Up | 0.0286812202 |
GSE28863_A1 | Down | -0.8683918112 |
GSE28863_A2 | Down | -0.3693791785 |
GSE28863_A3 | Up | 0.0799071089 |
GSE28863_A4 | Up | 0.0855314095 |
GSE48662 | Down | -0.2062625189 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
---|---|---|
Dextromethorphan | DB00514 | APRD00655 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-miR-124-3p | MIMAT0000422 | MIRT022884 | Microarray | Functional MTI (Weak) | 18668037 |
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