HCSGD entry for NCF2


1. General information

Official gene symbolNCF2
Entrez ID4688
Gene full nameneutrophil cytosolic factor 2
Other gene symbolsNCF-2 NOXA2 P67-PHOX P67PHOX
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001669Acrosomal vesicleIEAcellular_component
GO:0002474Antigen processing and presentation of peptide antigen via MHC class ITASbiological_process
GO:0002479Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependentTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006801Superoxide metabolic processTASbiological_process
GO:0006968Cellular defense responseTASbiological_process
GO:0007568AgingIEAbiological_process
GO:0008022Protein C-terminus bindingIPImolecular_function
GO:0009055Electron carrier activityTASmolecular_function
GO:0009749Response to glucoseIEAbiological_process
GO:0014823Response to activityIEAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0032010PhagolysosomeTAScellular_component
GO:0032496Response to lipopolysaccharideIEAbiological_process
GO:0032570Response to progesteroneIEAbiological_process
GO:0032870Cellular response to hormone stimulusIEAbiological_process
GO:0034616Response to laminar fluid shear stressIEAbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0042554Superoxide anion generationIEA TASbiological_process
GO:0042590Antigen processing and presentation of exogenous peptide antigen via MHC class ITASbiological_process
GO:0043020NADPH oxidase complexTAScellular_component
GO:0043525Positive regulation of neuron apoptotic processIEAbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0045730Respiratory burstTASbiological_process
GO:0045777Positive regulation of blood pressureIEAbiological_process
GO:0048365Rac GTPase bindingIEAmolecular_function
GO:0051701Interaction with hostTASbiological_process
GO:0055093Response to hyperoxiaIEAbiological_process
GO:0090382Phagosome maturationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.22210193000.15886530910.90345053250.7700200920

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1086952832
GSE13712_SHEARUp0.3027111848
GSE13712_STATICUp0.0217636174
GSE19018Down-0.0223128923
GSE19899_A1Down-0.1753959902
GSE19899_A2Up0.5374703973
PubMed_21979375_A1Up0.1912768919
PubMed_21979375_A2Down-0.2023727026
GSE35957Down-0.0814782539
GSE36640Up1.6719457822
GSE54402Down-0.3490201575
GSE9593Up0.1884742292
GSE43922Up0.0397520532
GSE24585Down-0.1057628379
GSE37065Up0.0286812202
GSE28863_A1Down-0.8683918112
GSE28863_A2Down-0.3693791785
GSE28863_A3Up0.0799071089
GSE28863_A4Up0.0855314095
GSE48662Down-0.2062625189

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

DextromethorphanDB00514 APRD00655

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022884MicroarrayFunctional MTI (Weak)18668037
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.