HCSGD entry for NCBP1

1. General information

Official gene symbolNCBP1
Entrez ID4686
Gene full namenuclear cap binding protein subunit 1, 80kDa
Other gene symbolsCBP80 NCBP Sto1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000184Nuclear-transcribed mRNA catabolic process, nonsense-mediated decayIDA IMP TASbiological_process
GO:0000339RNA cap bindingIEAmolecular_function
GO:0000387Spliceosomal snRNP assemblyTASbiological_process
GO:0000398MRNA splicing, via spliceosomeTASbiological_process
GO:0003723RNA bindingTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0005845MRNA cap binding complexIDAcellular_component
GO:0005846Nuclear cap binding complexIEAcellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0006368Transcription elongation from RNA polymerase II promoterTASbiological_process
GO:0006369Termination of RNA polymerase II transcriptionTASbiological_process
GO:00063707-methylguanosine mRNA cappingIDA TASbiological_process
GO:0006379MRNA cleavageIDAbiological_process
GO:0006406MRNA export from nucleusIMP TASbiological_process
GO:0006446Regulation of translational initiationIDAbiological_process
GO:0008334Histone mRNA metabolic processTASbiological_process
GO:0008380RNA splicingTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0030529Ribonucleoprotein complexIDAcellular_component
GO:0031047Gene silencing by RNAIEAbiological_process
GO:0031124MRNA 3'-end processingTASbiological_process
GO:0031442Positive regulation of mRNA 3'-end processingIDAbiological_process
GO:0034660NcRNA metabolic processTASbiological_process
GO:0045292MRNA cis splicing, via spliceosomeIEAbiological_process
GO:0050434Positive regulation of viral transcriptionTASbiological_process
GO:0051028MRNA transportIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.44196458720.23676063980.99999024730.9366989184

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1105577385
GSE13712_SHEARUp0.0707399130
GSE13712_STATICDown-0.1235816316
GSE19018Down-0.2528802657
GSE19899_A1Down-0.1511519757
GSE19899_A2Down-0.3652610812
PubMed_21979375_A1Down-0.1657516209
PubMed_21979375_A2Down-0.0852979480
GSE35957Down-0.3770151065
GSE36640Down-0.3531480513
GSE54402Up0.1432531493
GSE9593Down-0.3864110495
GSE43922Down-0.0332650476
GSE24585Up0.2512808443
GSE37065Down-0.2396772755
GSE28863_A1Up0.8160492871
GSE28863_A2Up0.4825326760
GSE28863_A3Down-0.1235996356
GSE28863_A4Up0.1811654418
GSE48662Up0.0221876352

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-215-5pMIMAT0000272MIRT024362MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026295MicroarrayFunctional MTI (Weak)19074876
hsa-miR-26b-5pMIMAT0000083MIRT028972MicroarrayFunctional MTI (Weak)19088304
hsa-let-7e-5pMIMAT0000066MIRT051610CLASHFunctional MTI (Weak)23622248
hsa-let-7a-5pMIMAT0000062MIRT052408CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.