HCSGD entry for NBL1
1. General information
| Official gene symbol | NBL1 |
|---|---|
| Entrez ID | 4681 |
| Gene full name | neuroblastoma 1, DAN family BMP antagonist |
| Other gene symbols | D1S1733E DAN DAND1 NB NO3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0007399 | Nervous system development | ISS | biological_process |
| GO:0016015 | Morphogen activity | ISS | molecular_function |
| GO:0035582 | Sequestering of BMP in extracellular matrix | ISS | biological_process |
| GO:0036122 | BMP binding | ISS | molecular_function |
| GO:0045666 | Positive regulation of neuron differentiation | ISS | biological_process |
| GO:0048263 | Determination of dorsal identity | ISS | biological_process |
| GO:0048812 | Neuron projection morphogenesis | ISS | biological_process |
| GO:0090027 | Negative regulation of monocyte chemotaxis | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0064356597 | 0.8854128757 | 0.2116718905 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.9105707040 |
| GSE13712_SHEAR | Down | -0.0757059893 |
| GSE13712_STATIC | Down | -0.1723845911 |
| GSE19018 | Down | -1.2626483964 |
| GSE19899_A1 | Up | 0.3054489378 |
| GSE19899_A2 | Up | 0.5014690664 |
| PubMed_21979375_A1 | Up | 1.4350756359 |
| PubMed_21979375_A2 | Up | 1.0437567012 |
| GSE35957 | Up | 0.0772276843 |
| GSE36640 | Up | 1.6419825790 |
| GSE54402 | Up | 0.4518468323 |
| GSE9593 | Up | 0.4083795087 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.2848513285 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT023164 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT024064 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025945 | Microarray | Functional MTI (Weak) | 19073608 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 7575554 | 17 beta-estradiol also enhanced the release of nitric oxide (NO) as measured by an NO selective meter and NO2-/NO3-, metabolites of NO, from endothelial cells |
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