HCSGD entry for PPP1R12B
1. General information
| Official gene symbol | PPP1R12B |
|---|---|
| Entrez ID | 4660 |
| Gene full name | protein phosphatase 1, regulatory subunit 12B |
| Other gene symbols | MYPT2 PP1bp55 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | biological_process |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006937 | Regulation of muscle contraction | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0008047 | Enzyme activator activity | TAS | molecular_function |
| GO:0015629 | Actin cytoskeleton | IDA | cellular_component |
| GO:0043085 | Positive regulation of catalytic activity | TAS | biological_process |
| GO:0050790 | Regulation of catalytic activity | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8549629801 | 0.2536630257 | 0.9999902473 | 0.9663454282 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2249022594 |
| GSE13712_SHEAR | Up | 0.0688872856 |
| GSE13712_STATIC | Up | 0.0384797389 |
| GSE19018 | Down | -0.0951777305 |
| GSE19899_A1 | Up | 0.0305890574 |
| GSE19899_A2 | Down | -0.2694848987 |
| PubMed_21979375_A1 | Down | -0.3748976112 |
| PubMed_21979375_A2 | Up | 0.0110612328 |
| GSE35957 | Down | -0.1815675130 |
| GSE36640 | Down | -0.1235396192 |
| GSE54402 | Down | -0.1879791428 |
| GSE9593 | Down | -0.1287605700 |
| GSE43922 | Down | -0.1989652066 |
| GSE24585 | Up | 0.0736879234 |
| GSE37065 | Down | -0.0231061631 |
| GSE28863_A1 | Up | 0.5910582326 |
| GSE28863_A2 | Down | -0.0451531861 |
| GSE28863_A3 | Up | 0.1046617207 |
| GSE28863_A4 | Down | -0.0704193135 |
| GSE48662 | Up | 0.1844184013 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30b-5p | MIMAT0000420 | MIRT046147 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
