HCSGD entry for MYO10

1. General information

Official gene symbolMYO10
Entrez ID4651
Gene full namemyosin X
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001726RuffleIEAcellular_component
GO:0003774Motor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005547Phosphatidylinositol-3,4,5-trisphosphate bindingISSmolecular_function
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005938Cell cortexIEAcellular_component
GO:0006200ATP catabolic processISSbiological_process
GO:0007165Signal transductionIEAbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0008152Metabolic processISSbiological_process
GO:0008360Regulation of cell shapeIMPbiological_process
GO:0016459Myosin complexIEAcellular_component
GO:0022409Positive regulation of cell-cell adhesionIEAbiological_process
GO:0030027LamellipodiumIEAcellular_component
GO:0030175FilopodiumIEAcellular_component
GO:0030705Cytoskeleton-dependent intracellular transportISSbiological_process
GO:0030898Actin-dependent ATPase activityISSmolecular_function
GO:0031527Filopodium membraneIEAcellular_component
GO:0032433Filopodium tipISScellular_component
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosisTASbiological_process
GO:0043005Neuron projectionIEAcellular_component
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0045087Innate immune responseTASbiological_process
GO:0051015Actin filament bindingISSmolecular_function
GO:0051489Regulation of filopodium assemblyIMPbiological_process
GO:0060002Plus-end directed microfilament motor activityISSmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02722640100.83486456440.38332142091.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1022448460
GSE13712_SHEARUp0.2233333346
GSE13712_STATICUp0.2681124355
GSE19018Down-0.0674778406
GSE19899_A1Up0.6669141674
GSE19899_A2Up0.2430827721
PubMed_21979375_A1Up1.0818464125
PubMed_21979375_A2Up0.7486722857
GSE35957Up0.1664409915
GSE36640Down-0.2215324954
GSE54402Up0.4408081784
GSE9593Down-0.2364875867
GSE43922Up0.2437227145
GSE24585Down-0.3440697167
GSE37065Up0.2390513417
GSE28863_A1Up0.2483316806
GSE28863_A2Up0.5638060489
GSE28863_A3Down-0.1671305820
GSE28863_A4Down-0.0238783165
GSE48662Down-0.1731507161

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT001532Luciferase reporter assay//qRT-PCR//Western blotFunctional MTI20427544
hsa-miR-155-5pMIMAT0000646MIRT001532pSILAC//ProteomicsFunctional MTI (Weak)18668040
hsa-miR-30a-5pMIMAT0000087MIRT005212pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-484MIMAT0002174MIRT041895CLASHFunctional MTI (Weak)23622248
hsa-miR-183-5pMIMAT0000261MIRT047146CLASHFunctional MTI (Weak)23622248
hsa-miR-26a-5pMIMAT0000082MIRT050130CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.