HCSGD entry for MYO9B

1. General information

Official gene symbolMYO9B
Entrez ID4650
Gene full namemyosin IXB
Other gene symbolsCELIAC4 MYR5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000146Microfilament motor activityIDAmolecular_function
GO:0001726RuffleIEAcellular_component
GO:0002548Monocyte chemotaxisIEAbiological_process
GO:0003774Motor activityIEAmolecular_function
GO:0003779Actin bindingIDAmolecular_function
GO:0005096GTPase activator activityIEAmolecular_function
GO:0005100Rho GTPase activator activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005516Calmodulin bindingIDAmolecular_function
GO:0005524ATP bindingIDA IEAmolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005938Cell cortexIDAcellular_component
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0007266Rho protein signal transductionICbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0015629Actin cytoskeletonTAScellular_component
GO:0016459Myosin complexIEAcellular_component
GO:0016887ATPase activityIDAmolecular_function
GO:0030010Establishment of cell polarityIEAbiological_process
GO:0030027LamellipodiumIEAcellular_component
GO:0030048Actin filament-based movementTASbiological_process
GO:0030898Actin-dependent ATPase activityIEAmolecular_function
GO:0031941Filamentous actinIDAcellular_component
GO:0032011ARF protein signal transductionIDAbiological_process
GO:0032433Filopodium tipIEAcellular_component
GO:0035556Intracellular signal transductionIEAbiological_process
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0043008ATP-dependent protein bindingIEAmolecular_function
GO:0043531ADP bindingIDAmolecular_function
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048246Macrophage chemotaxisIEAbiological_process
GO:0048471Perinuclear region of cytoplasmIDAcellular_component
GO:0051015Actin filament bindingIEAmolecular_function
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
GO:0072673Lamellipodium morphogenesisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.44313382850.44501682690.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2328520209
GSE13712_SHEARUp0.4763071781
GSE13712_STATICUp0.0630764163
GSE19018Up0.0549101900
GSE19899_A1Down-0.1817102902
GSE19899_A2Down-0.5432685599
PubMed_21979375_A1Down-0.0072312578
PubMed_21979375_A2Up0.3550163529
GSE35957Up0.0724919232
GSE36640Down-0.2088329886
GSE54402Up0.3390205830
GSE9593Up0.0563880567
GSE43922Down-0.0830197771
GSE24585Down-0.0244865260
GSE37065Up0.0567271500
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0699147281

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT019067MicroarrayFunctional MTI (Weak)18185580
hsa-miR-484MIMAT0002174MIRT042019CLASHFunctional MTI (Weak)23622248
hsa-miR-93-5pMIMAT0000093MIRT048837CLASHFunctional MTI (Weak)23622248
hsa-let-7e-5pMIMAT0000066MIRT051699CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.