HCSGD entry for MYO5A
1. General information
| Official gene symbol | MYO5A |
|---|---|
| Entrez ID | 4644 |
| Gene full name | myosin VA (heavy chain 12, myoxin) |
| Other gene symbols | GS1 MYH12 MYO5 MYR12 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000146 | Microfilament motor activity | NAS | molecular_function |
| GO:0001726 | Ruffle | IDA | cellular_component |
| GO:0001750 | Photoreceptor outer segment | IEA | cellular_component |
| GO:0003774 | Motor activity | IEA | molecular_function |
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005516 | Calmodulin binding | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005882 | Intermediate filament | IEA | cellular_component |
| GO:0006810 | Transport | NAS | biological_process |
| GO:0006887 | Exocytosis | IEA | biological_process |
| GO:0007268 | Synaptic transmission | IEA | biological_process |
| GO:0007601 | Visual perception | IEA | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016192 | Vesicle-mediated transport | ISS | biological_process |
| GO:0016459 | Myosin complex | IEA | cellular_component |
| GO:0017137 | Rab GTPase binding | IEA | molecular_function |
| GO:0030048 | Actin filament-based movement | NAS | biological_process |
| GO:0030073 | Insulin secretion | IEA | biological_process |
| GO:0030318 | Melanocyte differentiation | IEA | biological_process |
| GO:0030426 | Growth cone | NAS | cellular_component |
| GO:0031585 | Regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity | IEA | biological_process |
| GO:0031987 | Locomotion involved in locomotory behavior | IEA | biological_process |
| GO:0032252 | Secretory granule localization | IEA | biological_process |
| GO:0032402 | Melanosome transport | IEA | biological_process |
| GO:0032593 | Insulin-responsive compartment | ISS | cellular_component |
| GO:0032869 | Cellular response to insulin stimulus | ISS | biological_process |
| GO:0035371 | Microtubule plus-end | IEA | cellular_component |
| GO:0042438 | Melanin biosynthetic process | IEA | biological_process |
| GO:0042470 | Melanosome | IEA | cellular_component |
| GO:0042476 | Odontogenesis | IEA | biological_process |
| GO:0042552 | Myelination | IEA | biological_process |
| GO:0042640 | Anagen | IEA | biological_process |
| GO:0042641 | Actomyosin | IEA | cellular_component |
| GO:0042759 | Long-chain fatty acid biosynthetic process | IEA | biological_process |
| GO:0043005 | Neuron projection | NAS | cellular_component |
| GO:0043025 | Neuronal cell body | IEA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0050808 | Synapse organization | IEA | biological_process |
| GO:0051015 | Actin filament binding | IEA | molecular_function |
| GO:0051643 | Endoplasmic reticulum localization | IEA | biological_process |
| GO:0072659 | Protein localization to plasma membrane | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0037043691 | 0.9890472171 | 0.1633211055 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5870814351 |
| GSE13712_SHEAR | Down | -0.1697462279 |
| GSE13712_STATIC | Up | 0.0359401642 |
| GSE19018 | Up | 0.3233329236 |
| GSE19899_A1 | Up | 0.2658553834 |
| GSE19899_A2 | Up | 0.3020636923 |
| PubMed_21979375_A1 | Up | 0.2919601557 |
| PubMed_21979375_A2 | Up | 0.3947395580 |
| GSE35957 | Up | 0.6038872221 |
| GSE36640 | Up | 0.5684515639 |
| GSE54402 | Up | 0.1889785078 |
| GSE9593 | Up | 0.6317918688 |
| GSE43922 | Up | 0.0698626118 |
| GSE24585 | Down | -0.1955175294 |
| GSE37065 | Down | -0.0514930856 |
| GSE28863_A1 | Up | 0.9684523543 |
| GSE28863_A2 | Up | 1.7122045867 |
| GSE28863_A3 | Down | -0.3444289347 |
| GSE28863_A4 | Up | 0.0924173853 |
| GSE48662 | Up | 0.7615067746 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027083 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028356 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031724 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-145-5p | MIMAT0000437 | MIRT035535 | Luciferase reporter assay | Functional MTI | 22895360 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041583 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042081 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
