HCSGD entry for MYL6
1. General information
| Official gene symbol | MYL6 |
|---|---|
| Entrez ID | 4637 |
| Gene full name | myosin, light chain 6, alkali, smooth muscle and non-muscle |
| Other gene symbols | ESMLC LC17 LC17-GI LC17-NM LC17A LC17B MLC-3 MLC1SM MLC3NM MLC3SM |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003774 | Motor activity | TAS | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006200 | ATP catabolic process | ISS | biological_process |
| GO:0006936 | Muscle contraction | TAS | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0007519 | Skeletal muscle tissue development | TAS | biological_process |
| GO:0008152 | Metabolic process | ISS TAS | biological_process |
| GO:0008307 | Structural constituent of muscle | IDA | molecular_function |
| GO:0016459 | Myosin complex | TAS | cellular_component |
| GO:0016461 | Unconventional myosin complex | TAS | cellular_component |
| GO:0030049 | Muscle filament sliding | TAS | biological_process |
| GO:0030898 | Actin-dependent ATPase activity | ISS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8184160176 | 0.0755373504 | 0.9999902473 | 0.5192949426 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1552718518 |
| GSE13712_SHEAR | Up | 0.1147235633 |
| GSE13712_STATIC | Down | -0.0502744425 |
| GSE19018 | Down | -0.5419502741 |
| GSE19899_A1 | Down | -0.2401156469 |
| GSE19899_A2 | Up | 0.1782880730 |
| PubMed_21979375_A1 | Up | 0.1083932386 |
| PubMed_21979375_A2 | Down | -0.3265511898 |
| GSE35957 | Up | 0.1838948338 |
| GSE36640 | Up | 0.2516740420 |
| GSE54402 | Down | -0.0866900234 |
| GSE9593 | Up | 0.0063068659 |
| GSE43922 | Down | -0.2397752022 |
| GSE24585 | Up | 0.5843868557 |
| GSE37065 | Down | -0.2870028708 |
| GSE28863_A1 | Up | 0.1305224110 |
| GSE28863_A2 | Down | -0.5532898280 |
| GSE28863_A3 | Down | -0.4498318097 |
| GSE28863_A4 | Up | 0.1830545546 |
| GSE48662 | Down | -0.4511606538 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1910-5p | MIMAT0007884 | MIRT035801 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044318 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049263 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
