HCSGD entry for MYL3

1. General information

Official gene symbolMYL3
Entrez ID4634
Gene full namemyosin, light chain 3, alkali; ventricular, skeletal, slow
Other gene symbolsCMH8 MLC1SB MLC1V VLC1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002026Regulation of the force of heart contractionIMPbiological_process
GO:0003774Motor activityIEAmolecular_function
GO:0003785Actin monomer bindingIDAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005829CytosolTAScellular_component
GO:0005859Muscle myosin complexTAScellular_component
GO:0006942Regulation of striated muscle contractionIMPbiological_process
GO:0007519Skeletal muscle tissue developmentIEAbiological_process
GO:0008307Structural constituent of muscleTASmolecular_function
GO:0016459Myosin complexIEAcellular_component
GO:0030017SarcomereTAScellular_component
GO:0030049Muscle filament slidingTASbiological_process
GO:0031672A bandIDAcellular_component
GO:0031674I bandIDAcellular_component
GO:0032038Myosin II heavy chain bindingNASmolecular_function
GO:0032781Positive regulation of ATPase activityISSbiological_process
GO:0055010Ventricular cardiac muscle tissue morphogenesisIMPbiological_process
GO:0060048Cardiac muscle contractionIEA IMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.33778737130.78343483150.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0757427925
GSE13712_SHEARUp0.1961191074
GSE13712_STATICDown-0.0995006790
GSE19018Up0.0275457392
GSE19899_A1Up0.2603158653
GSE19899_A2Up0.0980936488
PubMed_21979375_A1Up0.1450636339
PubMed_21979375_A2Down-0.0645532466
GSE35957Up0.1328484121
GSE36640Up0.1786413679
GSE54402Up0.1303922156
GSE9593Down-0.2573276714
GSE43922Up0.0235736242
GSE24585Down-0.0666670110
GSE37065Up0.1898052469
GSE28863_A1Down-0.0451890009
GSE28863_A2Up0.3399808144
GSE28863_A3Up0.2224262857
GSE28863_A4Up0.1380679439
GSE48662Down-0.6439962414

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.