HCSGD entry for MYH10

1. General information

Official gene symbolMYH10
Entrez ID4628
Gene full namemyosin, heavy chain 10, non-muscle
Other gene symbolsNMMHC-IIB NMMHCB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000146Microfilament motor activityIDAmolecular_function
GO:0000281Mitotic cytokinesisIDA IEAbiological_process
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0001725Stress fiberIDA IEAcellular_component
GO:0001764Neuron migrationIEAbiological_process
GO:0001778Plasma membrane repairIEAbiological_process
GO:0003774Motor activityIEAmolecular_function
GO:0003779Actin bindingNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005524ATP bindingIDA IEA NASmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005819SpindleIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0005938Cell cortexIDA IEAcellular_component
GO:0006200ATP catabolic processIDAbiological_process
GO:0006887ExocytosisIEAbiological_process
GO:0006930Substrate-dependent cell migration, cell extensionIEAbiological_process
GO:0007097Nuclear migrationIEAbiological_process
GO:0007155Cell adhesionIEAbiological_process
GO:0007411Axon guidanceIEA TASbiological_process
GO:0007512Adult heart developmentIEAbiological_process
GO:0008152Metabolic processIDAbiological_process
GO:0008283Cell proliferationIEAbiological_process
GO:0008360Regulation of cell shapeIEAbiological_process
GO:0016459Myosin complexIEA NAScellular_component
GO:0016460Myosin II complexIEAcellular_component
GO:0021592Fourth ventricle developmentIEAbiological_process
GO:0021670Lateral ventricle developmentIEAbiological_process
GO:0021678Third ventricle developmentIEAbiological_process
GO:0021680Cerebellar Purkinje cell layer developmentIEAbiological_process
GO:0030027LamellipodiumIEAcellular_component
GO:0030048Actin filament-based movementIDAbiological_process
GO:0030424AxonIEAcellular_component
GO:0030426Growth coneIEAcellular_component
GO:0030496MidbodyIDAcellular_component
GO:0030898Actin-dependent ATPase activityIDAmolecular_function
GO:0031594Neuromuscular junctionIEAcellular_component
GO:0032154Cleavage furrowIDAcellular_component
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0043197Dendritic spineIEAcellular_component
GO:0043531ADP bindingIDAmolecular_function
GO:0050885Neuromuscular process controlling balanceIEAbiological_process
GO:0051015Actin filament bindingIDA IEAmolecular_function
GO:0055003Cardiac myofibril assemblyIEAbiological_process
GO:0055015Ventricular cardiac muscle cell developmentIEAbiological_process
GO:0060041Retina development in camera-type eyeIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97388660770.00002325900.99999024730.0085375000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-2.9725826404
GSE13712_SHEARDown-0.9592708417
GSE13712_STATICDown-1.8178149563
GSE19018Down-1.8063652328
GSE19899_A1Down-2.1686388578
GSE19899_A2Down-3.5222518508
PubMed_21979375_A1Down-2.6290976945
PubMed_21979375_A2Down-3.3086896979
GSE35957Down-0.1865016492
GSE36640Down-1.7773310979
GSE54402Down-1.5676071941
GSE9593Down-0.3498342938
GSE43922Down-2.1836250339
GSE24585Down-0.0782201020
GSE37065Down-0.7671346016
GSE28863_A1Up0.5563120331
GSE28863_A2Up0.7503605014
GSE28863_A3Up0.2240098777
GSE28863_A4Up0.0077826812
GSE48662Down-0.1308057548

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-106b-3pMIMAT0004672MIRT038556CLASHFunctional MTI (Weak)23622248
hsa-miR-92b-3pMIMAT0003218MIRT040548CLASHFunctional MTI (Weak)23622248
hsa-miR-505-3pMIMAT0002876MIRT041051CLASHFunctional MTI (Weak)23622248
hsa-miR-197-3pMIMAT0000227MIRT048126CLASHFunctional MTI (Weak)23622248
hsa-miR-26a-5pMIMAT0000082MIRT050174CLASHFunctional MTI (Weak)23622248
hsa-miR-23a-3pMIMAT0000078MIRT050395CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.