HCSGD entry for MYH2

1. General information

Official gene symbolMYH2
Entrez ID4620
Gene full namemyosin, heavy chain 2, skeletal muscle, adult
Other gene symbolsMYH2A MYHSA2 MYHas8 MyHC-2A MyHC-IIa
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000146Microfilament motor activityTASmolecular_function
GO:0001778Plasma membrane repairIEAbiological_process
GO:0003774Motor activityIEAmolecular_function
GO:0003779Actin bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0005826Actomyosin contractile ringIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005859Muscle myosin complexNAS TAScellular_component
GO:0005925Focal adhesionIDAcellular_component
GO:0006936Muscle contractionIDA TASbiological_process
GO:0008152Metabolic processTASbiological_process
GO:0008307Structural constituent of muscleNASmolecular_function
GO:0014823Response to activityIEAbiological_process
GO:0016459Myosin complexIEAcellular_component
GO:0030016MyofibrilIDAcellular_component
GO:0030017SarcomereNAScellular_component
GO:0030049Muscle filament slidingNASbiological_process
GO:0031672A bandIEAcellular_component
GO:0032982Myosin filamentIEAcellular_component
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosisTASbiological_process
GO:0043234Protein complexIDAcellular_component
GO:0045087Innate immune responseTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.52399088560.56937263020.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0808062220
GSE13712_SHEARUp0.0097460538
GSE13712_STATICUp0.2167378617
GSE19018Down-0.0031655801
GSE19899_A1Up0.1042669058
GSE19899_A2Up0.2387018489
PubMed_21979375_A1Up0.1360542278
PubMed_21979375_A2Up0.0187393649
GSE35957Up1.4954341113
GSE36640Up0.1053519478
GSE54402Down-0.1537176224
GSE9593Down-0.3950393704
GSE43922Up0.0132665551
GSE24585Down-0.2946021033
GSE37065Down-0.0147964593
GSE28863_A1Down-0.0543088346
GSE28863_A2Down-0.0487682566
GSE28863_A3Up0.0879107187
GSE28863_A4Down-0.0215135643
GSE48662Up0.0169653913

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-23a-3pMIMAT0000078MIRT006908Luciferase reporter assay//qRT-PCR//Western blotFunctional MTI22771720
hsa-miR-92a-3pMIMAT0000092MIRT048977CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.