HCSGD entry for MYH1
1. General information
| Official gene symbol | MYH1 |
|---|---|
| Entrez ID | 4619 |
| Gene full name | myosin, heavy chain 1, skeletal muscle, adult |
| Other gene symbols | MYHSA1 MYHa MyHC-2X/D MyHC-2x |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003774 | Motor activity | IEA | molecular_function |
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005516 | Calmodulin binding | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005859 | Muscle myosin complex | IDA | cellular_component |
| GO:0005925 | Focal adhesion | IDA | cellular_component |
| GO:0006936 | Muscle contraction | IEA | biological_process |
| GO:0014704 | Intercalated disc | IEA | cellular_component |
| GO:0031672 | A band | IEA | cellular_component |
| GO:0032982 | Myosin filament | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2739662057 | 0.9329341438 | 0.9702724031 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0826130421 |
| GSE13712_SHEAR | Up | 0.1108816155 |
| GSE13712_STATIC | Up | 0.1139762035 |
| GSE19018 | Up | 0.0904932864 |
| GSE19899_A1 | Up | 0.1787868073 |
| GSE19899_A2 | Up | 0.0925438459 |
| PubMed_21979375_A1 | Up | 0.3360634042 |
| PubMed_21979375_A2 | Down | -0.2106661310 |
| GSE35957 | Up | 1.4607450925 |
| GSE36640 | Down | -0.0114598781 |
| GSE54402 | Up | 0.0036473141 |
| GSE9593 | Up | 0.0126489639 |
| GSE43922 | Up | 0.0191952488 |
| GSE24585 | Up | 0.2180618354 |
| GSE37065 | Down | -0.0268082926 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.0378916959 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-23a-3p | MIMAT0000078 | MIRT006907 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 22771720 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
