HCSGD entry for MYBPC3

1. General information

Official gene symbolMYBPC3
Entrez ID4607
Gene full namemyosin binding protein C, cardiac
Other gene symbolsCMH4 FHC MYBP-C
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001671ATPase activator activityISSmolecular_function
GO:0002027Regulation of heart rateIEAbiological_process
GO:0003007Heart morphogenesisIMPbiological_process
GO:0003779Actin bindingIEAmolecular_function
GO:0005829CytosolTAScellular_component
GO:0005863Striated muscle myosin thick filamentIDA ISScellular_component
GO:0006942Regulation of striated muscle contractionISSbiological_process
GO:0007155Cell adhesionIEAbiological_process
GO:0008307Structural constituent of muscleIMPmolecular_function
GO:0014705C zoneNAScellular_component
GO:0017022Myosin bindingIDAmolecular_function
GO:0030017SarcomereIDAcellular_component
GO:0030049Muscle filament slidingTASbiological_process
GO:0031034Myosin filament assemblyIEAbiological_process
GO:0031432Titin bindingNASmolecular_function
GO:0031672A bandIDAcellular_component
GO:0032036Myosin heavy chain bindingIPImolecular_function
GO:0032781Positive regulation of ATPase activityISSbiological_process
GO:0032971Regulation of muscle filament slidingISSbiological_process
GO:0042802Identical protein bindingIPImolecular_function
GO:0045214Sarcomere organizationIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0055010Ventricular cardiac muscle tissue morphogenesisIMPbiological_process
GO:0060048Cardiac muscle contractionISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.65583915500.53311740820.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1091368442
GSE13712_SHEARUp0.0850222699
GSE13712_STATICUp0.0411061021
GSE19018Down-0.0123896049
GSE19899_A1Down-0.0632368771
GSE19899_A2Up0.0261815033
PubMed_21979375_A1Up0.0052242925
PubMed_21979375_A2Down-0.1043352274
GSE35957Up0.2913204827
GSE36640Up0.2031355131
GSE54402Down-0.0386234674
GSE9593Down-0.0098850110
GSE43922Up0.0419536493
GSE24585Up0.0314899457
GSE37065Down-0.1084195603
GSE28863_A1Down-0.3582005543
GSE28863_A2Down-0.2181313324
GSE28863_A3Up0.4419824653
GSE28863_A4Up0.0964373325
GSE48662Up0.0287867932

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.