HCSGD entry for MX2


1. General information

Official gene symbolMX2
Entrez ID4600
Gene full namemyxovirus (influenza virus) resistance 2 (mouse)
Other gene symbolsMXB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003924GTPase activityIEAmolecular_function
GO:0005525GTP bindingIEA IMPmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005643Nuclear poreIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006184GTP catabolic processTASbiological_process
GO:0006952Defense responseTASbiological_process
GO:0008152Metabolic processTASbiological_process
GO:0009615Response to virusIDAbiological_process
GO:0015031Protein transportIEAbiological_process
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0035455Response to interferon-alphaIDAbiological_process
GO:0046822Regulation of nucleocytoplasmic transportIMPbiological_process
GO:0051028MRNA transportIEAbiological_process
GO:0051607Defense response to virusIMPbiological_process
GO:0051726Regulation of cell cycleIMPbiological_process
GO:0060337Type I interferon signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00081238170.39141483990.07972205881.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1182711103
GSE13712_SHEARUp7.0504733656
GSE13712_STATICUp6.1224682972
GSE19018Down-0.0026785134
GSE19899_A1Up0.3231711788
GSE19899_A2Down-0.3155092317
PubMed_21979375_A1Up0.1348741101
PubMed_21979375_A2Down-0.0684288103
GSE35957Down-3.4256863479
GSE36640Down-0.0770691880
GSE54402Down-0.1528757460
GSE9593Up0.1841378955
GSE43922Down-0.1097309818
GSE24585Up0.7086293553
GSE37065Up1.6739096343
GSE28863_A1Up0.5180787402
GSE28863_A2Up1.4615785206
GSE28863_A3Up0.2416401596
GSE28863_A4Down-0.0639574686
GSE48662Up0.1870304316

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-146a-5pMIMAT0000449MIRT021267MicroarrayFunctional MTI (Weak)18057241
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.