HCSGD entry for MST1R


1. General information

Official gene symbolMST1R
Entrez ID4486
Gene full namemacrophage stimulating 1 receptor (c-met-related tyrosine kinase)
Other gene symbolsCD136 CDw136 PTK8 RON
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001725Stress fiberIEAcellular_component
GO:0004713Protein tyrosine kinase activityIEAmolecular_function
GO:0004872Receptor activityIEAmolecular_function
GO:0005011Macrophage colony-stimulating factor receptor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006928Cellular component movementTASbiological_process
GO:0006952Defense responseTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007169Transmembrane receptor protein tyrosine kinase signaling pathwayIEAbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0007338Single fertilizationTASbiological_process
GO:0008284Positive regulation of cell proliferationTASbiological_process
GO:0009615Response to virusIDAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0018108Peptidyl-tyrosine phosphorylationTASbiological_process
GO:0019899Enzyme bindingIPImolecular_function
GO:0038145Macrophage colony-stimulating factor signaling pathwayTASbiological_process
GO:0043406Positive regulation of MAP kinase activityIDAbiological_process
GO:0045087Innate immune responseIEAbiological_process
GO:0051897Positive regulation of protein kinase B signalingIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.58624597850.81693583450.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0262175585
GSE13712_SHEARUp0.0732509570
GSE13712_STATICUp0.0290310331
GSE19018Up0.0060052235
GSE19899_A1Down-0.2642336930
GSE19899_A2Up0.0012118580
PubMed_21979375_A1Up0.1006346165
PubMed_21979375_A2Up0.2259111981
GSE35957Down-0.0384618409
GSE36640Up0.0681221927
GSE54402Down-0.0120338696
GSE9593Down-0.1020687488
GSE43922Up0.0225938055
GSE24585Up0.2036519288
GSE37065Up0.0068213090
GSE28863_A1Down-0.0754424824
GSE28863_A2Up0.1382795672
GSE28863_A3Up0.2179632395
GSE28863_A4Up0.1552964185
GSE48662Up0.0577828753

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.